Genetic Risk Score Correlates with Immune Profile and Risk of HCC and Cirrhosis development in Hispanics with MASLD

Abstract
Genetic risk score and immune dysregulations have been separately associated with the development of hepatocellular carcinoma (HCC) and cirrhosis in the context of metabolic associated steatotic liver disease (MASLD). Latin America has the highest prevalence of MASLD worldwide. However, the relationship between genetic risk scores, immune dysregulation and MASLD has not been explored.
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