Microwave-assisted synthesis and regioisomeric structural elucidation of novel benzimidazo[1,2d][1,4]benzodiazepinone derivatives

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dc.contributor.authorPessoa Mahana, David
dc.contributor.authorEspinosa Bustos, Christian
dc.contributor.authorMella Raipan, Jaime
dc.contributor.authorCanales Pacheco, Jorge
dc.contributor.authorPessoa Mahana, Hernan
dc.date.accessioned2024-01-10T13:50:35Z
dc.date.available2024-01-10T13:50:35Z
dc.date.issued2009
dc.description.abstractThe synthesis of 5H-benzimidazo [1,2-d] [1,4] benzodiazepin -6(7H)-ones 3a-e from readily available 2-(2-aminophenyl)-1H-benzo[d]imidazole derivatives 2a-e and 2-bromoacetyl bromide under microwave conditions is described. Unambiguous structural elucidation of the obtained regioisomers was finally established by means of 2D-NOESY experiment.
dc.description.funderVRAID
dc.fechaingreso.objetodigital2024-05-30
dc.format.extent10 páginas
dc.fuente.origenWOS
dc.identifier.doi10.3998/ark.5550190.0010.c11
dc.identifier.eissn1551-7012
dc.identifier.issn1551-7004
dc.identifier.urihttps://doi.org/10.3998/ark.5550190.0010.c11
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79541
dc.identifier.wosidWOS:000273295600011
dc.information.autorucQuímica;Canales-Pacheco J;S/I;149392
dc.information.autorucQuímica;Espinosa-Bustos C;S/I;142011
dc.information.autorucQuímica;Mella-Raipán J;S/I;126011
dc.information.autorucQuímica;Pessoa-Mahana D;S/I;76905
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final140
dc.pagina.inicio131
dc.publisherARKAT USA INC
dc.revistaARKIVOC
dc.rightsacceso restringido
dc.subjectHeterocycles
dc.subjectbenzimidazoles
dc.subjectbenzodiazepines
dc.subjectmicrowaves
dc.subjectBIOLOGICAL-ACTIVITY
dc.subjectANTITUMOR-ACTIVITY
dc.subjectANALOGS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMicrowave-assisted synthesis and regioisomeric structural elucidation of novel benzimidazo[1,2d][1,4]benzodiazepinone derivatives
dc.typeartículo
sipa.codpersvinculados149392
sipa.codpersvinculados142011
sipa.codpersvinculados126011
sipa.codpersvinculados76905
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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