Microwave-Assisted Reaction of 2,3-Dichloronaphthoquinone with Aminopyridines
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Date
2009
Journal Title
Journal ISSN
Volume Title
Publisher
SOC BRASILEIRA QUIMICA
Abstract
The synthesis of pyridylaminonaphthoquinones by microwave-assisted reaction of 2,3-dichloro1,4-naphthoquinone with aminopyridines is described. The use of microwave irradiation diminished the reaction times and improved the yields substantially in all these reactions. The compounds were tested for their cytotoxic activities against MCF-7 breast cancer cell line.
Description
Keywords
2,3-dichloronaphthoquinone, microwave irradiation, aminopyridines, cytotoxic activity, ORGANIC-SYNTHESIS, DERIVATIVES, QUINONES