The synthesis of pyridylaminonaphthoquinones by microwave-assisted reaction of 2,3-dichloro1,4-naphthoquinone with aminopyridines is described. The use of microwave irradiation diminished the reaction times and improved the yields substantially in all these reactions. The compounds were tested for their cytotoxic activities against MCF-7 breast cancer cell line.
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Autor | Tapia, Ricardo A. Cantuarias, Lorena Cuellar, Mauricio Villena, Joan |
Título | Microwave-Assisted Reaction of 2,3-Dichloronaphthoquinone with Aminopyridines |
Revista | JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY |
ISSN | 0103-5053 |
ISSN electrónico | 1678-4790 |
Volumen | 20 |
Número de publicación | 5 |
Página inicio | 999 |
Página final | 1002 |
Fecha de publicación | 2009 |
Resumen | The synthesis of pyridylaminonaphthoquinones by microwave-assisted reaction of 2,3-dichloro1,4-naphthoquinone with aminopyridines is described. The use of microwave irradiation diminished the reaction times and improved the yields substantially in all these reactions. The compounds were tested for their cytotoxic activities against MCF-7 breast cancer cell line. |
Derechos | registro bibliográfico |
Agencia financiadora | FONDECYT CONICYT |
DOI | 10.1590/S0103-50532009000500027 |
Editorial | SOC BRASILEIRA QUIMICA |
Enlace | |
Id de publicación en WoS | WOS:000266403500027 |
Paginación | 4 páginas |
Palabra clave | 2,3-dichloronaphthoquinone microwave irradiation aminopyridines cytotoxic activity ORGANIC-SYNTHESIS DERIVATIVES QUINONES |
Tema ODS | 03 Good Health and Well-being |
Tema ODS español | 03 Salud y bienestar |
Tipo de documento | artículo |