Artículos de revistas

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Esta colección incluye artículos de revistas de profesores de la Pontificia Universidad Católica de Chile, publicados en revistas nacionales y extranjeras.

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Análisis comparativo y perfil de publicaciones en la Revista Chilena de Pediatría 2001-2006
(2007) Harris, Paul R.; Liebbe G., J.L.; Sotomayor A., J.; Ugarte P., F.; Cano Sch., F.
Background: The Revista Chilena de Pediatría (Rev Chil Pediatr), official journal of Sociedad Chilena de Pediatría is index in SciELO, but not in the National Library of Medicine (NLM) of USA. Objectives: a) Determine the profile of published and visited articles of Rev Chil Ped, in order to compare them with the Jornal de Pediatria from Brazil (J Ped Br) and the Journal of Pediatrics (J Ped) from USA. b) Evaluate the visibility of Rev Chil Pediatr compared to Revista Medica de Chile (Rev Med Chil). Method: On line issues from the above mentioned journal were evaluated through SciELO database and PubMed database from 2001 - 2006. A random and representative subset of published articles was obtained from each one of the 3 journals during the referred period. The most visited articles from Rev Chil Pediatr were analyzed and classified as originals (clinical and basic research) and non originals (editorial, clinical case, reviews and others). The articles were classified according to thematic content in 25 medical specialties. In addition, the number of annual visits to Rev Chil Pediatr and Rev Med Chil were analyzed, including the most frequent citations given and received in that period of time. Results: Out of 512 articles in Rev Chil Pediatr, 220 were analyzed; 35% were originals and 65% non originals, with a significant lower percentage of original articles compared to J Ped Br and J Ped (p < 0.05). The thematic areas with more articles were respiratory disease, infectious diseases and nutrition with 9.1, 7.7 and 7.7%, respectively. Rev Chil Pediatr published twice as many nutrition articles and five times more public health articles compared to J Ped (p < 0.05). The most visited articles on line were of nutrition, infectious diseases, respiratory diseases and neonatology. Among the 10 most visited articles from Rev Chil Pediatr, 7 were review articles. Since 2005, an explosive growth is detected in the number of visits to articles from Rev Chil Pediatr in SciELO. When the number of visits was adjusted to the number of physicians belonging to the corresponding society, there was a higher number of visits to Rev Chil Pediatr from 2005 compared to Rev Med Chile. Conclusion: The thematic content of Rev Chil Pediatr is similar to regional journals, but different to international ones. There is an appropriate correlation between published and visited articles. SciELO has been an important tool that contributes to the diffusion of research published in Rev Chil Pediatr. © 2007 Sociedad Chilena de Pediatría.
Correlación genotipo-fenotipo de un grupo de pacientes con fibrosis quística
(Soc. Médica Santiago, 2002) Navarro M., Héctor; Kolbach Rengifo, Marianne Helene; Repetto Lisboa, María Gabriela; Guiraldes Cameratti, Ernesto; Harris D., Paul R.; Foradori, Arnaldo; Poggi, Helena; Sánchez Díaz, Ignacio
Background: Cystic fibrosis (CF) is the most common lethal autosomic disease in Caucasians, with a global incidence of 1:3000 newborns. More than 900 mutations have been described, involving the Cystic Fibrosis Transmembrane Regulator (CFTR). The delta F508 mutation is present in 60% of alleles studied worldwide.Aim: To report 25 patients with cystic fibrosis in whom a genetic study was done.Material and methods: Twenty five patients (14 men, aged between 18 months and 25 years) with a diagnosis of cystic fibrosis based on clinical features plus two abnormal sweat tests are reported. The genetic study considered the 20 most common mutations in cystic fibrosis and was done in genomic DNA of peripheral lymphocytes, by polymerase chain reaction.Results: A mutation was found in 75% of analyzed alleles. delta F508 was present in 50% of cases (delta F508/delta F508 in 8 and delta F508/other in 11). When delta F508 was present, pancreatic insufficiency was always a feature and nutritional status was worse. Respiratory involvement was variable, both for homozygous and heterozygous cases. Other severe mutations such as W128X and G542X were related to clinical manifestations similar to those found in delta F508 mutation. Diagnosis was made before six months of age in 12 patients. The clinical presentation was meconium ileus and there was a family history of the disease in most cases. The majority of cases of early diagnosis presented severe mutations, but milder respiratory symptoms and lesser nutritional compromise at the time of assessment.Conclusions: Most patients studied had a severe cystic fibrosis mutation, which was associated with more severe respiratory, pancreatic and nutritional involvement. The early diagnosis of the disease, which would allow to improve the prognosis and the quality of life, must be emphasized.
Esofagitis eosinofílica en niños: Características clínicas y endoscópicas
(2009) González, Carmen Gloria; Torres, Javiera; Molina, Ricardo; Harris, Paul R.
Estrategias de prevención de infecciones tardías en unidades de cuidados intensivos neonatales
(2019) Toso, Alberto
Introducción: la sepsis tardía (ST) sigue siendo un problema relevante en las unidades de cuidados intensivos de neonatología (UCIN), especialmente en recién nacidos (RN) menores de 1500 g o RN de muy bajo peso al nacer (RNMBPN). Método: se realizó una búsqueda de la mejor evidencia disponible respecto a las estrategias de prevención de infecciones en unidades de cuidados intensivos neonatales. Resultados: se han descrito diversas estrategias para intentar disminuir su incidencia, entre estas se incluye el uso de vacunas en el embarazo, profilaxis con fluconazol y uso de probióticos. Han demostrado utilidad otras medidas destinadas a reducir y racionalizar el uso de antibióticos, la creación de equipos especializados y la incorporación de bundles a la práctica clínica. Conclusiones: Este artículo resume la evidencia actualmente disponible y proporciona herramientas que pueden ser utilizadas en la práctica cotidiana dentro de las UCIN.
Fog water collection for local greenhouse vegetable production in the Atacama Desert
(2023) Albornoz G., Francisco; Río López, Camilo del; Carter Gamberini, María Virginia; Escobar Moragas, Rodrigo; Vásquez Gimeno, Lucas Simón
Agricultural production in the Atacama Desert is restricted by extreme aridity and poor soil quality. Between 18° S and 30° S, low stratocumulus clouds regularly cover the southeastern Pacific Ocean reaching the Coastal Cordillera. Thus, marine fog is constantly present in the coastal areas of the desert. Fog can be harvested using fog collectors. However, limited information is available with regards to the variability of fog presence throughout the year and along the coast of the desert. Combining fog water harvest with hydroponic production under greenhouse facilities presents an alternative for sustainable and local fresh food production. In this article, we analyze the potential of fog water collection in two sites (Alto Patache and Falda Verde) distant by about 1000 km within the Atacama Desert. Additionally, in both locations, the environmental conditions within greenhouse structures, the potential energy requirement for environmental conditioning (including the energy production from photovoltaic panels) and the water requirements of vegetable crops under greenhouse conditions were modeled. The annual average of fog water collection registered was 2.9 and 3.3 L per day per m2 in Alto Patache and Falda Verde, respectively. During the most demanding season for crop evapotranspiration, 2.13 m2 of fog collectors can supply the water required for 1 m2 of greenhouse crops. The energy required for water and air pumps in the hydroponic systems can be supplied with photovoltaic systems including eight PV modules and a battery storage capacity of 9.4 kWh. In conclusion, the present study sheds light on the possibilities of massive water collection from fog to be used in local and sustainable food production in the Atacama Desert.
Individual Behavior Modeling with Sensors Using Process Mining
(2019) Dogan, Onur; Martinez-Millana, Antonio; Rojas, Eric; Sepúlveda Fernández, Marcos Ernesto; Muñoz Gama, Jorge; Traver, Vicente; Fernandez-Llatas, Carlos
Understanding human behavior can assist in the adoption of satisfactory healthinterventions and improved care. One of the main problems relies on the definition of humanbehaviors, as human activities depend on multiple variables and are of dynamic nature. Althoughsmart homes have advanced in the latest years and contributed to unobtrusive human behaviortracking, artificial intelligence has not coped yet with the problem of variability and dynamismof these behaviors. Process mining is an emerging discipline capable of adapting to the nature ofhigh-variate data and extract knowledge to define behavior patterns. In this study, we analyze datafrom 25 in-house residents acquired with indoor location sensors by means of process miningclustering techniques, which allows obtaining workflows of the human behavior inside the house.Data are clustered by adjusting two variables: the similarity index and the Euclidean distancebetween workflows. Thereafter, two main models are created: (1) a workflow view to analyze thecharacteristics of the discovered clusters and the information they reveal about human behaviorand (2) a calendar view, in which common behaviors are rendered in the way of a calendarallowing to detect relevant patterns depending on the day of the week and the season of the year.Three representative patients who performed three different behaviors: stable, unstable, and complexbehaviors according to the proposed approach are investigated. This approach provides humanbehavior details in the manner of a workflow model, discovering user paths, frequent transitionsbetween rooms, and the time the user was in each room, in addition to showing the results into thecalendar view increases readability and visual attraction of human behaviors, allowing to us detectpatterns happening on special days.
Microstructure of starch-based meals with either palm or soybean oils alter in vitro starch digestibility with no major effects on glycaemic responses
(2019) Bravo, Carolina; Santos Martín, José Luis; Castillo, Gabriel; Olivares, Gabriela; Parada, Javier
Glycaemic response (GR) to starch-based meals depends on their food composition and microstructure. We studied the effect of palm and soybean oils on the microstructure of a solid starch-oil-gluten matrix, on the starch gelatinisation and in vitro digestibility. Additionally, a pilot cross-over study was carried out to assess GR after eating gelatinised starch/gluten-based foods with the addition of either palm or soybean oil in 8 young non-diabetic female volunteers (ISRCTN39636850). Both types of foods generated similar starch gelatinisation temperature. Starch/gluten-based food with soybean oil had rougher microstructure compared to food with palm oil, showing a higher initial and lower final in vitro digestion. Administration of starch/gluten-based meals with either palm or soybean oils to volunteers show very similar postprandial glucose or insulin responses. In conclusion, differences in fatty acid composition changes food microstructure and in vitro starch digestibility, with no major effects on glycaemic responses in female volunteers.
Obesity is associated with early recurrence on breast cancer patients that achieved pathological complete response to neoadjuvant chemotherapy
(2022) Acevedo Claros, Francisco Nicolás; Walbaum García, Benjamín Vicente; Muñiz Muñoz, María Sabrina; Petric Guajardo, Militza Paulina; Martínez, Raúl; Guerra, Constanza; Navarro, Marisel; Córdova Delgado, Miguel; Pinto, Mauricio P.; Sánchez Rojel, César Giovanni
Pathological complete response (pCR) after neoadjuvant chemotherapy (NCT) is associated with good long-term prognosis in breast cancer (BC) patients. However, some patients still recur and eventually die from this disease. For years, clinical stage at diagnosis has been consistently linked to recurrence and survival in the pCR setting. Herein, we aimed to identify other potential predictors of recurrence and survival in patients that achieved pCR. We performed a retrospective analysis of patients diagnosed between 2011 and 2020 in our center. We calculated overall survival (OS), invasive disease-free survival (IDFS), distant disease-free survival (DDFS), and BC-specific survival (BCSS). Among the 241 patients included into our study 36% were obese (Body Mass Index (BMI) > 29.9 kg/m2) and 47% were stage III. Multivariate analysis confirmed that obesity was a significant risk factor associated with early recurrence and poorer survival in these patients. In summary, obesity and clinical stage predict early recurrence and poorer survival in patients that achieved pCR after NCT. Pending further investigation and based on our findings we speculate that weight management could be beneficial for this subset of patients. To our knowledge, this is the first Latin American report linking obesity and recurrence within this setting.
Pathological complete response to neoadjuvant chemotherapy, but not the addition of carboplatin, is associated with improved survival in Chilean triple negative breast cancer patients: a report of real world data
(2021) Walbaum, Benjamin; Acevedo, Francisco; Median, Lidia; Bravo, M. Loreto; Merino, Tomas; Camus, Mauricio; Dominguez, Francisco; Mondaca, Sebastián; Galindo, Héctor; Nervi, Bruno; Ibañez, Carolina; Madrid, Jorge; Muñiz, Sabrina; Peña, José; Koch, Érica; Garrido, Marcelo; Pinto, Mauricio P.; Sánchez, César
Background: Breast cancer (BC) is the leading cause of cancer death for Chilean women. About 11% of cases are triple-negative (TN) BC. These are characterised by poor prognosis, higher risk of early recurrence and visceral dissemination versus other BC subtypes. Current standard treatment for early-stage non-metastatic TNBC patients consists of neoadjuvant chemotherapy (NACT) followed by surgery and radiotherapy. Pathological complete response (pCR) to NACT is associated with an increase in survival rates. In general, NACT and adjuvant regimens involve similar cytotoxic drugs. Recent studies have postulated that the use of platinum compounds in TNBC would increase response rates. However, their effects on patient survival remain uncertain. Materials and methods: We retrieved and analysed medical records from a total of 156 Chilean stage I–III TNBC female patients that received NACT and compared survival rates using carboplatin (Cb)-containing versus non-Cb-containing regimens at two health cancer centres. Results: Median age was 51 years (range: 24–81); 13.5% (n = 21) received Cb-containing regimens, 80.1% (n = 125) received sequential anthracyclines plus taxanes; 29.5% (n = 46) of the total group achieved pCR, 28% for the standard treatment and 35% (n = 8) for the Cb-containing group (p = 0.59). We confirmed pCR was associated with prolonged overall survival, invasive and distant disease-free survival (Log-rank p = 0.0236). But the addition of Cb was not associated with differences in survival measures (Log-rank p = 0.5216). Conclusions: To the best of authors’ knowledge, this is the first report on real-world data in the Chilean population assessing the effect of Cb-containing NACT in TNBC. The authors’ results suggest no survival benefit by the addition of Cb to standard NACT. However, we confirm an increase in survival associated to pCR regardless of treatment.
Religious Coping, Experiential Avoidance, Self‑Compassion, and Post‑Traumatic Stress by COVID‑19: a Serial Mediation Study
(2023) Fuentes-Ferrada, Reiner; Cerda-Planas, Catalina; Fernández, María Beatriz
The COVID-19 pandemic has brought consequences to mental health, with religiosity being a relevant coping factor in reducing the negative impact of the health crisis. Based on a convenience sample of Chilean adults, this study sought to explore the relationship between religious coping and post-traumatic stress due to COVID-19, hypothesizing that this relationship would be mediated by experiential avoidance and self-compassion. A non-experimental cross-sectional design was used, applying an online survey to 300 adults who lived in Chile. The results show that all variables are related and that experiential avoidance (EA) and self-compassion play a serial mediating role in the relationship between negative religious coping (NRC) and post-traumatic stress. Furthermore, the results showed that religious coping, experiential avoidance, self-compassion, and COVID-19 post-traumatic stress are signifcantly interrelated. Moreover, a serial mediation was found among the variables: higher experiential avoidance and lower level of self-compassion mediate the impact of COVID-19 post-traumatic stress in people with negative religious coping. At the end of the article, the implications of the results and how these variables interact in a serial mediation mechanism that sheds further light on the relationships between negative religious coping, mental health, and adverse situations such as COVID-19 are discussed.
Respuesta y recuperación ante desastres: complejidades institucionales y técnicas en contextos de post-terremoto en Chile
(Corporation for the Management and Reduction of Disaster Risk in Chile (GRID-Chile), 2023) Mella-Lira B.; Vigouroux, Orlando; Meneses Ferrada, Camilo Ignacio; Aguirre C.; Encinas Pino, Felipe; Bertholet, Patricio
Los eventos sísmicos pueden causar un daño importante a inmuebles públicos y privados y son vital importancia para la gestión pública. En este contexto, es relevante reconocer los actores y los momentos críticos que experimentan las organizaciones que coordinan las labores de respuesta, rescate, recopilación de datos y deliberación de traslados. En Chile, la toma de decisiones sobre estos procesos involucra a tres ministerios: el Ministerio de Desarrollo Social recopila la información de las personas y las familias afectadas por la emergencia; el Ministerio de Vivienda y Urbanismo catastra información para asignar beneficios transitorios o definitivos de vivienda; y el Ministerio del Interior, quien a través del Servicio Nacional de Prevención y Respuesta ante Desastres (SENAPRED), planifica y coordina los recursos públicos y privados para gestionar el manejo de la emergencia. Al momento de la crisis se suman otros grupos: voluntarios, unidades de bomberos, carabineros, agrupaciones de la sociedad civil, empresas aseguradoras, entre otros. El artículo explora las complejidades institucionales y técnicas que participan de la primera respuesta luego de un sismo (ej. toma de datos, sistematización, análisis y toma de decisiones).
Screen-detected breast cancer is associated with better prognosis and survival compared to self-detected/symptomatic cases in a Chilean cohort of female patients
(2021) Walbaum, Benjamin; Puschel, Klaus; Medina, Lidia; Merino, Tomas; Camus, Mauricio; Razmilic, Dravna; Navarro, Maria Elena; Dominguez, Francisco; Cordova‑Delgado, Miguel; Pinto, Mauricio P.; Acevedo, Francisco; Sánchez, César
Purpose The implementation of national breast cancer (BC) screening programs in Latin America has been rather inconsistent. Instead, most countries have opted for “opportunistic” mammogram screenings on the population at risk. Our study assessed and compared epidemiological, clinical factors, and survival rates associated with BC detected by screening (SDBC) or self-detected/symptomatic (non-SDBC) in Chilean female patients. Methods Registry-based cohort study that included non-metastatic BC (stage I/II/III) patients diagnosed between 1993 and 2020, from a public hospital (PH) and a private university cancer center (PC). Epidemiological and clinical data were obtained from medical records. Results A total of 4559 patients were included. Most patients (55%; n = 2507) came from PH and were diagnosed by signs/ symptoms (non-SDBC; n = 3132, 68.6%); these patients displayed poorer overall (OS) and invasive disease-free survival (iDFS) compared to SDBC. Importantly, the proportion of stage I and “luminal” BC (HR + /HER2 −) were significantly higher in SDBC vs. non-SDBC. Finally, using a stage/subset-stratified age/insurance-adjusted model, we found that nonSDBC cases are at a higher risk of death (HR:1.75; p < 0.001). In contrast, patients with PC health insurance have a lower risk of death (HR: 0.60; p < 0.001). Conclusion We confirm previous studies that report better prognosis/survival on SDBC patients. This is probably due to a higher proportion of stage I and luminal-A cases versus non-SDBC. In turn, the survival benefit observed in patients with PC health insurance might be attributed to a larger proportion of SDBC. Our data support the implementation of a systematic BC screening program in Chile to improve patient prognosis and survival rates.
Sedación, Seguridad y Utilidad de la Endoscopia Digestiva Alta en Pediatría
(2010) Riera C., Francisca; González F., Carmen Gloria; Vaca Z., Carina; Marchant A., Pamela; Glenz A., Constanza; Larraín B., Francisco; Harris R., Paul
Introducción: El estudio endoscópico alto es un procedimiento diagnóstico y terapéutico considerado de rutina, pero su realización en pediatría se encuentra limitada dada la necesidad de sedación y monitoreo adecuados. Objetivos: Evaluar la sedación, indicación y percepción de los padres del examen. Materiales y Métodos: Estudio prospectivo de 190 niños sometidos a endoscopia digestiva alta. Se obtuvieron datos biodemográficos, tipo de sedación y resultados del examen. Resultados: La edad fue 8,5 + 4,2 años, la mayoría referidos por pediatra (60%). La principal indicación del estudio fue el dolor abdominal recurrente (29,8%). Los pacientes fueron clasificados de acuerdo al ASA (93% ASA I y II). En la mayoría se requirió de 2 ó más drogas para lograr sedación óptima. La calidad del procedimiento fue satisfactoria en más del 90%. Un 75,5% presentaron amnesia completa y un 42,7% molestias leves posterior al procedimiento. Entre los hallazgos destacaron signos de esofagitis en el 13,9%, observándose un 61% de los exámenes normales. Al analizar los pacientes por peso (mayores y menores de 14 kg), se encontraron diferencias en edad (p < 0,00001), ASA (p = 0,001), indicación de endoscopia (p = 0,001) y evaluación de la sedación por enfermera (p = 0,038). Conclusión: Procedimientos endoscópicos en niños pueden realizarse de manera segura en forma ambulatoria mediante sedación moderada. Una adecuada monitorización y conocimiento de técnicas de reanimación son básicos al momento de realizar dichos procedimientos.
Serological diagnosis of Helicobacter pylori infection in children
(2005) Harris, Paul R.; Serrano H., C.; González F., C.G.
Helicobacter pylori (H. pylori) colonizes 50% of the world's population. The infection is acquired during infancy; an age group of non-invasive diagnostic methods need to be urgently validated. Our aim was to review the literature and evaluate the usefulness of serological diagnosis with special emphasis on the paediatric population. The relevance of these methods has been focused in epidemiological studies. In adult populations, the determination of antibodies against H. pylori exhibits a sensitivity and specificity of over 90%, being comparable to other invasive endoscopy based methods. In the paediatric population, the performance of serological testing has been less successful, with lower sensitivity and specificity. This underlies the need to establish more precise cut off values, based on local populations, where studies using antibodies as diagnostic markers of H. pylori are planned.
Síndromes por microdeleción
(2004) Mellado S., Cecilia
Socioeconomic, Clinical, and Molecular Features of Breast Cancer Influence Overall Survival of Latin American Women
(2022) de Almeida, Liz Maria; Cortés Arancibia, Sandra; Vilensky, Marta; Valenzuela, Olivia; Cortes-Sanabria, Laura; de Souza, Mirian; Alonso Barbeito, Rafael; Abdelhay, Eliana; Artagaveytia, Nora; Daneri-Navarro, Adrian; Llera, Andrea S.; Muller, Bettina; Podhajcer, Osvaldo L.; Velazquez, Carlos; Alcoba, Elsa; Alonso, Isabel; Bravo, Alicia, I; Camejo, Natalia; Maria Carraro, Dirce; Castro, Monica; Cataldi, Sandra; Cayota, Alfonso; Cerda, Mauricio; Colombo, Alicia; Crocamo, Susanne; Del Toro-Arreola, Alicia; Delgadillo-Cristerna, Raul; Delgado, Lucia; Breitenbach, Marisa Dreyer; Fernandez, Elmer; Fernandez, Jorge; Fernandez, Wanda; Franco-Topete, Ramon A.; Gaete, Fancy; Gomez, Jorge; Gonzalez-Ramirez, Leivy P.; Guerrero, Marisol; Gutierrez-Rubio, Susan A.; Jalfin, Beatriz; Lopez-Vazquez, Alejandra; Loria, Dora; Miguez, Silvia; Moran-Mendoza, Andres de J.; Morgan-Villela, Gilberto; Mussetti, Carina; Nagai, Maria Aparecida; Oceguera-Villanueva, Antonio; Reis, Rui M.; Retamales, Javier; Rodriguez, Robinson; Rosales, Cristina; Salas-Gonzalez, Efrain; Segovia, Laura; Sendoya, Juan M.; Silva-Garcia, Aida A.; Vina, Stella; Zagame, Livia; Jones, Beth; Szklo, Moyses
Molecular profile of breast cancer in Latin-American women was studied in five countries: Argentina, Brazil, Chile, Mexico, and Uruguay. Data about socioeconomic characteristics, risk factors, prognostic factors, and molecular subtypes were described, and the 60-month overall cumulative survival probabilities (OS) were estimated. From 2011 to 2013, 1,300 eligible Latin-American women 18 years or older, with a diagnosis of breast cancer in clinical stage II or III, and performance status not less than or equal to 1 were invited to participate in a prospective cohort study. Face-to-face interviews were conducted, and clinical and outcome data, including death, were extracted from medical records. Unadjusted associations were evaluated by Chi-squared and Fisher's exact tests and the OS by Kaplan-Meier method. Log-rank test was used to determine differences between cumulative probability curves. Multivariable adjustment was carried out by entering potential confounders in the Cox regression model. The OS at 60 months was 83.9%. Multivariable-adjusted death hazard differences were found for women living in Argentina (2.27), Chile (1.95), and Uruguay (2.42) compared with Mexican women, for older (>= 60 years) (1.84) compared with younger (<= 40 years) women, for basal-like subtype (5.8), luminal B (2.43), and HER2-enriched (2.52) compared with luminal A subtype, and for tumor clinical stages IIB (1.91), IIIA (3.54), and IIIB (3.94) compared with stage IIA women. OS was associated with country of residence, PAM50 intrinsic subtype, age, and tumor stage at diagnosis. While the latter is known to be influenced by access to care, including cancer screening, timely diagnosis and treatment, including access to more effective treatment protocols, it may also influence epigenetic changes that, potentially, impact molecular subtypes. Data derived from heretofore understudied populations with unique geographic ancestry and sociocultural experiences are critical to furthering our understanding of this complexity.
Superficial angiomyxoma of the skin
(2016) Abarzúa, Alvaro; Lallas, Aimillios; Piana, Simonetta; Longo, Caterina; Moscarella, Elvira; Argenziano, Giuseppe
Superficial angiomyxomas (SA) of the skin are rare benign cutaneous tumors of soft tissue composedof prominent myxoid matrix and numerous blood vessels. SA are more common in males [1] and theyare usually located on the trunk but can also appear on the lower limbs, head, neck and genitalia [2,3].Treatment is surgical, the total excision is curative, but local recurrence is possible [4]. Herein wepresent a 72-year-old patient with a history of melanoma in situ, with a new lesion on the lower back.

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