Fructose, Omega 3 Fatty Acids, and Vitamin E: Involvement in Pediatric Non-Alcoholic Fatty Liver Disease

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dc.catalogadorpau
dc.contributor.authorAlberti, Gigliola
dc.contributor.authorGana, Juan Cristóbal
dc.contributor.authorSantos, José L.
dc.date.accessioned2024-01-19T19:22:43Z
dc.date.available2024-01-19T19:22:43Z
dc.date.issued2020
dc.description.abstractNon-alcoholic fatty liver disease (NAFLD) is currently the most common form of liver disease in both adults and children, becoming the leading cause for liver transplant in many countries. Its prevalence has increased considerably in recent years, mainly due to the explosive increase in pediatric obesity rates. NAFLD is strongly associated with central obesity, diabetes, dyslipidemia and insulin resistance, and it has been considered as the hepatic manifestation of the metabolic syndrome. Its complex pathophysiology involves a series of metabolic, inflammatory and oxidative stress processes, among others. Given the sharp increase in the prevalence of NAFLD and the lack of an appropriate pharmacological approach, it is crucial to consider the prevention/management of the disease based on lifestyle modifications such as the adoption of a healthy nutrition pattern. Herein, we review the literature and discuss the role of three key nutrients involved in pediatric NAFLD: fructose and its participation in metabolism, Omega-3 fatty acids and its anti-inflammatory effects and vitamin E and its action on oxidative stress.
dc.fechaingreso.objetodigital2024-04-11
dc.fuente.origenORCID-ene24
dc.identifier.doi10.3390/nu12113531
dc.identifier.issn0718-4182
dc.identifier.urihttps://doi.org/10.3390/nu12113531
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80827
dc.information.autorucEscuela de Medicina; Santos Martin, Jose Luis; 0000-0003-2895-0369; 1005923
dc.issue.numero11
dc.language.isoen
dc.nota.accesoContenido completo
dc.revistaNutrients
dc.rightsacceso abierto
dc.subjectNonalcoholic fatty liver disease (NAFLD)es_ES
dc.subjectNASHes_ES
dc.subjectNutritiones_ES
dc.subjectSteatosises_ES
dc.subjectSugares_ES
dc.subjectFructosees_ES
dc.subjectOmega 3 fatty acidses_ES
dc.subjectVitamin Ees_ES
dc.titleFructose, Omega 3 Fatty Acids, and Vitamin E: Involvement in Pediatric Non-Alcoholic Fatty Liver Diseasees_ES
dc.titleFructose, Omega 3 Fatty Acids, and Vitamin E: Involvement in Pediatric Non-Alcoholic Fatty Liver Disease
dc.typeartículo
dc.volumen12
sipa.codpersvinculados1005923
sipa.trazabilidadORCID;2024-01-08
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