Daño vascular asociado a uso de cocaína. Caso clínico
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Date
2012
Journal Title
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Volume Title
Publisher
SOC MEDICA SANTIAGO
Abstract
Cocaine abuse is associated with an increased risk of cardiac and cerebro vascular events, such as myocardial infarction, sudden cardiac death, and ischemic stroke. The underlying mechanisms leading to these complications are not fully understood although intravascular thrombus formation and accelerated atherosclerosis are prominent findings. We report a 39-year-old male addicted to cocaine, who presented with three consecutive ischemic events characterized by an acute myocardial infarction and two ischemic strokes complicated by cardiac failure and severe neurological sequelae. The pathophysiology of cocaine-induce vascular damage and the management of the ischemic complications are discussed. (Rev Med Chile 2012; 140: 507-511).
Description
Keywords
Cocaine, Endothelium, vascular, Myocardial infarction, MYOCARDIAL-INFARCTION, CARDIOVASCULAR COMPLICATIONS, ENDOTHELIAL DYSFUNCTION, CHEST-PAIN, HEART, PLATELET, STROKE