Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024

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dc.contributor.authorFerreccio Readi, Catterina
dc.contributor.authorRoa Strauch, Juan Carlos Enrique
dc.contributor.authorBambs S., Claudia
dc.contributor.authorVives Vergara, Alejandra
dc.contributor.authorCorvalán R., Alejandro
dc.contributor.authorCortés Arancibia, Sandra
dc.contributor.authorFoerster, Claudia.
dc.contributor.authorAcevedo, Johanna.
dc.contributor.authorHuidobro, Andrea.
dc.contributor.authorPassi Solar, Alvaro Rodrigo
dc.date.accessioned2019-10-17T10:54:29Z
dc.date.available2019-10-17T10:54:29Z
dc.date.issued2016
dc.date.updated2019-10-14T18:33:06Z
dc.description.abstractAbstract Background Maule Cohort (MAUCO), a Chilean cohort study, seeks to analyze the natural history of chronic diseases in the agricultural county of Molina (40,000 inhabitants) in the Maule Region, Chile. Molina´s population is of particular interest because in the last few decades it changed from being undernourished to suffering excess caloric intake, and it currently has the highest national rates of cardiovascular diseases, stomach cancer and gallbladder cancer. Between 2009 and 2011 Molina´s poverty rate dropped from 24.1 % to 13.5 % (national average 20.4 %); in this period the county went from insufficient to almost complete basic sanitation. Despite these advances, chemical pollutants in the food and air are increasing. Thus, in Molina risk factors typical of both under-developed and developed countries coexist, generating a unique profile associated with inflammation, oxidative stress and chronic diseases. Methods/Design MAUCO is the core project of the recently established Advanced Center for Chronic Diseases (ACCDiS), Universidad de Chile & Pontificia Universidad Católica de Chile. In this study, we are enrolling and following 10,000 adults aged 38 to 74 years over 10 years. All eligible Molina residents will be enrolled. Participants were identified through a household census. Consenting individuals answer an epidemiological survey exploring risk factors (psycho-social, pesticides, diet, alcohol, and physical activity), medical history and physical and cognitive conditions; provide fasting blood, urine, and saliva samples; receive an electrocardiogram, abdominal ultrasound and bio-impedance test; and take a hand-grip strength test. These subjects will be re-interviewed after 2, 5 and 7 years. Active surveillance of health events is in place throughout the regional healthcare system. The MAUCO Bio-Bank will store 30 to 50 aliquots per subject using an NIH/NCI biorepository system for secure and anonymous linkage of samples with data. Discussion MAUCO´s results will help design public health interventions tailored to agricultural populations in Latin America.
dc.fuente.origenBiomed Central
dc.identifier.citationBMC Public Health. 2016 Feb 04;16(1):122
dc.identifier.doi10.1186/s12889-015-2454-2
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/26578
dc.issue.numeroNo. 122
dc.language.isoen
dc.pagina.final7
dc.pagina.inicio1
dc.revistaBMC Public Healthes_ES
dc.rightsacceso abierto
dc.rights.holderFerreccio et al.
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.otherEnfermedades crónicases_ES
dc.subject.otherEpidemiologíaes_ES
dc.subject.otherMaule (Chile : Provincia)es_ES
dc.titleStudy protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024es_ES
dc.typeartículo
dc.volumenVol. 16
sipa.codpersvinculados99684
sipa.codpersvinculados84743
sipa.codpersvinculados89631
sipa.codpersvinculados135637
sipa.codpersvinculados63885
sipa.codpersvinculados1005970
sipa.codpersvinculados141613
sipa.codpersvinculados155739
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