Accuracy of invasive and noninvasive tests to diagnose Helicobacter pylori infection after antibiotic treatment

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dc.contributor.authorRollan, A
dc.contributor.authorGiancaspero, R
dc.contributor.authorArrese, M
dc.contributor.authorFigueroa, C
dc.contributor.authorVollrath, V
dc.contributor.authorSchultz, M
dc.contributor.authorDuarte, I
dc.contributor.authorVial, P
dc.date.accessioned2024-01-10T12:04:05Z
dc.date.available2024-01-10T12:04:05Z
dc.date.issued1997
dc.description.abstractObjectives: To compare the diagnostic accuracy of the most widely available tests for diagnosis of Helicobacter pylori infection after antibiotic treatment, Methods: A total of 59 H, pylori-positive, duodenal ulcer patients (mean age, 40.7 +/- 11.7 yr; 40 male and 19 female) were treated for 2 wk with either amoxicillin-metronidazole (n = 36) or omeprazole-amoxicillin-tinidazole (n = 23), and after 4 wk, were tested for H, pylori infection by [C-14]urea breath test (UBT), serum IgG antibody level, and multiple antral biopsies for rapid urease testing, histology, Warthin-Starry stain, and polymerase chain reaction to detect H, pylori DNA, Infection status was established by a concordance of test results, Results: H, pylori was eradicated in 47 patients (80%), UBT and rapid urease testing had the best sensitivity and specificity, although not statistically different to Warthin-Starry stain and polymerase chain reaction, Serology and histology had little diagnostic value in this setting due to high proportion of false-positive results, Conclusions: Noninvasive UBT is as accurate in predicting H, pylori status after antibiotic treatment as rapid urease testing and Warthin-Starry stain, Especially for duodenal ulcer patients, UBT could be considered the gold standard to confirm eradication of H, pylori.
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.issn0002-9270
dc.identifier.pubmedidMEDLINE:9260787
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75680
dc.identifier.wosidWOS:A1997XP75600006
dc.information.autorucMedicina;Arrese M;S/I;76095
dc.issue.numero8
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final1274
dc.pagina.inicio1268
dc.publisherWILLIAMS & WILKINS
dc.revistaAMERICAN JOURNAL OF GASTROENTEROLOGY
dc.rightsregistro bibliográfico
dc.subjectPOLYMERASE CHAIN-REACTION
dc.subjectRAPID UREASE TEST
dc.subjectBREATH TEST
dc.subjectSYDNEY SYSTEM
dc.subjectSHORT-TERM
dc.subjectERADICATION
dc.subjectOMEPRAZOLE
dc.subjectSEROPREVALENCE
dc.subjectASSOCIATION
dc.subjectGASTRITIS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAccuracy of invasive and noninvasive tests to diagnose Helicobacter pylori infection after antibiotic treatment
dc.typeartículo
dc.volumen92
sipa.codpersvinculados76095
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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