Dyslipidemia in seven Latin American cities: CARMELA study
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Date
2010
Journal Title
Journal ISSN
Volume Title
Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
Abstract
Objective. The objective of this study was to describe the prevalence of dyslipidemia in the CARMELA study population.
Methods. CARMELA was a cross-sectional study of cardiovascular risk conducted between September 2003 and August 2005 in adults (aged 25 to 64 years) living in Barquisimeto (n = 1,824), Bogot (n = 1,511), Buenos Aires (n = 1,412), Lima (n = 1,628), Mexico City (n = 1,677), Quito (n = 1,620), and Santiago (n = 1,605). Dyslipidemia was defined as the presence of one or more of the following conditions: triglycerides >= 200 mg/dL, or total cholesterol (TC) >= 240 mg/dL, or HDL cholesterol < 40 mg/dL, or LDL cholesterol = not optimal, or currently taking antilipemic agents.
Results. Prevalence rates of dyslipidemia in men and women were: 75.5% (CI: 71.9-79.1) and 48.7% (CI: 45.4-51.9) in Barquisimeto: 70% (CI: 66.2-73.8) and 47.7% (CI: 43.9-51.5) in Bogota; 50.4% (CI: 46.8-54.0) and 24.1% (CI: 21.0-27.2) in Buenos Aires: 73.1% (CI: 69.3-76.8) and 62.8% (CI: 59.2-66.5) in Lima; 62.5% (CI: 58.5-66.5) and 37.5% (CI: 33.5-41.6) in Mexico City; 52.2% (CI: 47.9-56.5) and 38.1% (CI: 34.5-41.7) in Quito: and, 50.8% (CI: 47.1-54.4) and 32.8% (CI: 29.3-36.3) in Santiago.
Conclusions. Dyslipidemia was disturbingly prevalent and varied across cities. The most frequent dyslipidemia was low HDL-C followed by high triglycerides. The high TC/HDL-C ratios and non-HDL-C levels suggest a high risk of cardiovascular disease. (C) 2009 Elsevier Inc. All rights reserved.
Methods. CARMELA was a cross-sectional study of cardiovascular risk conducted between September 2003 and August 2005 in adults (aged 25 to 64 years) living in Barquisimeto (n = 1,824), Bogot (n = 1,511), Buenos Aires (n = 1,412), Lima (n = 1,628), Mexico City (n = 1,677), Quito (n = 1,620), and Santiago (n = 1,605). Dyslipidemia was defined as the presence of one or more of the following conditions: triglycerides >= 200 mg/dL, or total cholesterol (TC) >= 240 mg/dL, or HDL cholesterol < 40 mg/dL, or LDL cholesterol = not optimal, or currently taking antilipemic agents.
Results. Prevalence rates of dyslipidemia in men and women were: 75.5% (CI: 71.9-79.1) and 48.7% (CI: 45.4-51.9) in Barquisimeto: 70% (CI: 66.2-73.8) and 47.7% (CI: 43.9-51.5) in Bogota; 50.4% (CI: 46.8-54.0) and 24.1% (CI: 21.0-27.2) in Buenos Aires: 73.1% (CI: 69.3-76.8) and 62.8% (CI: 59.2-66.5) in Lima; 62.5% (CI: 58.5-66.5) and 37.5% (CI: 33.5-41.6) in Mexico City; 52.2% (CI: 47.9-56.5) and 38.1% (CI: 34.5-41.7) in Quito: and, 50.8% (CI: 47.1-54.4) and 32.8% (CI: 29.3-36.3) in Santiago.
Conclusions. Dyslipidemia was disturbingly prevalent and varied across cities. The most frequent dyslipidemia was low HDL-C followed by high triglycerides. The high TC/HDL-C ratios and non-HDL-C levels suggest a high risk of cardiovascular disease. (C) 2009 Elsevier Inc. All rights reserved.
Description
Keywords
Dyslipidemia, Urban population, Cross-sectional studies, Latin America, DENSITY-LIPOPROTEIN CHOLESTEROL, CORONARY-HEART-DISEASE, ACUTE MYOCARDIAL-INFARCTION, RISK-FACTORS, CARDIOVASCULAR-DISEASE, GLOBAL BURDEN, FOLLOW-UP, PREVALENCE, PREVENTION, INTERVENTIONS