Volitional regulation of the supplementary motor area with fMRI-BCI neurofeedback in Parkinson's disease: A pilot study
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Date
2013
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Journal ISSN
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Publisher
IEEE
Abstract
It is hypothesized that a dysfunction of the supplementary motor area (SMA), secondary to a deficit of the nigrostriatal dopamine system, partially contributes to the symptomatology of Parkinson's disease (PD), i.e., akinesia. In this pilot study we investigated the effect of real-time fMRI neurofeedback based volitional up-regulation of the SMA on hand motor performance of one PD patient and 3 healthy volunteers. The effect of learned self-regulation was evaluated with speeded, bimanual, sequenced button-pressing trials, assessed immediately after each baseline and up-regulation block. Our pilot results indicate that volitional up-regulation of SMA is accompanied by slowing of sequenced button presses.
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Keywords
Thumb, Neurofeedback, Parkinson's disease, Presses, Training, Educational institutions