Interplay between Lipid Metabolism, Lipid Droplets, and DNA Virus Infections

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dc.catalogadorjwg
dc.contributor.authorFarias, Mónica A.
dc.contributor.authorDiethelm-Varela, Benjamín
dc.contributor.authorNavarro, Areli J.
dc.contributor.authorKalergis Parra, Alexis Mikes
dc.contributor.authorGonzález, Pablo A.
dc.date.accessioned2024-01-26T15:02:55Z
dc.date.available2024-01-26T15:02:55Z
dc.date.issued2022
dc.description.abstractLipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and cholesterol esters that are coated by a phospholipid monolayer and associated proteins. LDs are known to play important roles in the storage and availability of lipids in the cell and to serve as a source of energy reserve for the cell. However, these structures have also been related to oxidative stress, reticular stress responses, and reduced antigen presentation to T cells. Importantly, LDs are also known to modulate viral infection by participating in virus replication and assembly. Here, we review and discuss the interplay between neutral lipid metabolism and LDs in the replication cycle of different DNA viruses, identifying potentially new molecular targets for the treatment of viral infections.
dc.fechaingreso.objetodigital2024-05-28
dc.fuente.origenWOS
dc.identifier.doi10.3390/cells11142224
dc.identifier.eissn2073-4409
dc.identifier.urihttp://doi.org/10.3390/cells11142224
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80986
dc.identifier.wosidWOS:000833611100001
dc.issue.numero14
dc.language.isoen
dc.nota.accesoContenido completo
dc.publisherMDPI
dc.revistaCELLS
dc.rightsacceso abierto
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleInterplay between Lipid Metabolism, Lipid Droplets, and DNA Virus Infections
dc.typeartículo
dc.volumen11
sipa.trazabilidadORCID;2024-01-15
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