Mechanical Power of Ventilation: From Computer to Clinical Implications

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dc.catalogadorjca
dc.contributor.authorDamiani Rebolledo, L. Felipe
dc.contributor.authorBasoalto Escobar, Roque Ignacio
dc.contributor.authorRetamal Montes, Jaime Alejandro
dc.contributor.authorBruhn Cruz, Alejandro Rodrigo
dc.contributor.authorBugedo Tarraza, Guillermo Jaime
dc.date.accessioned2023-12-29T14:15:17Z
dc.date.available2023-12-29T14:15:17Z
dc.date.issued2023
dc.description.abstractMechanical ventilation is a lifesaving intervention that may also induce further lung injury by exerting excessive mechanical forces on susceptible lung tissue, a phenomenon termed ventilator-induced lung injury (VILI). The concept of mechanical power (MP) aims to unify in one single variable the contribution of the different ventilatory parameters that could induce VILI by measuring the energy transfer to the lung over time. Despite an increasing amount of evidence demonstrating that high MP values can be associated with VILI development in experimental studies, the evidence regarding the association of MP and clinical outcomes remains controversial. In the present review, we describe the different determinants of VILI, the concept and computation of MP, and discuss the experimental and clinical studies related to MP. Currently, due to different limitations, the clinical application of MP is debatable. Further clinical studies are required to enhance our understanding of the relationship between MP and the development of VILI, as well as its potential impact on clinical outcomes.
dc.fechaingreso.objetodigital2023-12-29
dc.fuente.origenSCOPUS
dc.fuente.origenORCID
dc.identifier.doi10.4187/respcare.11462
dc.identifier.issn19433654
dc.identifier.scopusidSCOPUS_ID:85177976923
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75585
dc.information.autorucEscuela de Medicina; Damiani Rebolledo, L. Felipe; S/I; 237645
dc.information.autorucEscuela de Medicina; Basoalto Escobar, Roque Ignacio; S/I; 1010703
dc.information.autorucEscuela de Medicina; Retamal Montes, Jaime Alejandro; 0000-0002-6817-3659; 175147
dc.information.autorucEscuela de Medicina; Bruhn Cruz, Alejandro Rodrigo; S/I; 741
dc.information.autorucEscuela de Medicina; Bugedo Tarraza, Guillermo Jaime; 0000-0001-7527-6202; 60490
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final1756
dc.pagina.inicio1748
dc.revistaRespiratory care
dc.rightsacceso restringido
dc.subjectEnergy
dc.subjectMechanical power
dc.subjectMechanical ventilation
dc.subjectVILI
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMechanical Power of Ventilation: From Computer to Clinical Implications
dc.typeartículo
dc.volumen68
sipa.codpersvinculados237645
sipa.codpersvinculados1010703
sipa.codpersvinculados175147
sipa.codpersvinculados741
sipa.codpersvinculados60490
sipa.trazabilidadSCOPUS;2023-12-10
sipa.trazabilidadORCID;2023-12-25
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