Update on the Mechanisms of Pulmonary Inflammation and Oxidative Imbalance Induced by Exercise

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dc.contributor.authorAraneda, O. F.
dc.contributor.authorCarbonell, T.
dc.contributor.authorTuesta Roa, Marcelo
dc.date.accessioned2020-01-12T02:22:30Z
dc.date.available2020-01-12T02:22:30Z
dc.date.issued2016
dc.description.abstractThe mechanisms involved in the generation of oxidative damage and lung inflammation induced by physical exercise are described. Changes in lung function induced by exercise involve cooling of the airways, fluid evaporation of the epithelial surface, increased contact with polluting substances, and activation of the local and systemic inflammatory response. The present work includes evidence obtained from the different types of exercise in terms of duration and intensity, the effect of both acute performance and chronic performance, and the influence of special conditions such as cold weather, high altitude, and polluted environments. Levels of prooxidants, antioxidants, oxidative damage to biomolecules, and cellularity, as well as levels of soluble mediators of the inflammatory response and its effects on tissues, are described in samples of lung origin. These samples include tissue homogenates, induced sputum, bronchoalveolar lavage fluid, biopsies, and exhaled breath condensate obtained in experimental protocols conducted on animal and human models. Finally, the need to simultaneously explore the oxidative/inflammatory parameters to establish the interrelation between them is highlighted.
dc.format.extent1 página
dc.fuente.origenFacultad de Medicina
dc.identifier.doi10.1155/2016/4868536
dc.identifier.issn1942-0900
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/27237
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.inicio23
dc.revistaOxidative Medicine and Cellular Longevityes_ES
dc.rightsacceso abierto
dc.subjectexhaled breath condensatees_ES
dc.subjectcross-country skierses_ES
dc.subjectnonasthmatic amateures_ES
dc.subjectrunnerses_ES
dc.subjectadolescent elite swimmerses_ES
dc.subjecthigh-intensity exercisees_ES
dc.subjectnitric-oxide productiones_ES
dc.subjectairway inflammationes_ES
dc.subjectlipid-peroxidationes_ES
dc.subjectmoderate exercisees_ES
dc.subjectcystic-fibrosises_ES
dc.subjectCell Biologyes_ES
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleUpdate on the Mechanisms of Pulmonary Inflammation and Oxidative Imbalance Induced by Exercisees_ES
dc.typeartículo
sipa.codpersvinculados1015160
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