Total/HDL cholesterol ratio and non HDL cholesterol as predictors for increased intima media thickness

Simple item page
dc.contributor.authorAcevedo, Monica
dc.contributor.authorKraemer, Veronica
dc.contributor.authorTagle, Rodrigo
dc.contributor.authorCorbalan, Ramon
dc.contributor.authorArnaiz, Pilar
dc.contributor.authorBerrios, Ximena
dc.contributor.authorNavarrete, Carlos
dc.date.accessioned2024-01-10T13:44:00Z
dc.date.available2024-01-10T13:44:00Z
dc.date.issued2012
dc.description.abstractBackground: LDL, HDL cholesterol and triglycerides, are the most commonly used lipid cardiovascular risk predictor indicators. However population based studies have shown that non-HDL cholesterol and total/HDL cholesterol ratio are better predictors, are easy to measure and do not require fasting. Aim: To determine which lipid indicators are better determinants of subclinical atherosclerosis, measured by intima media thickness (IMT) among subjects without demonstrated atherosclerosis. Material and Methods: Lipid profile, height, weight, blood pressure and bilateral IMT measured by ultrasound with automatic border recognition software, were assessed in 770 men and 854 women aged 45 +/- 11 years, in Santiago de Chile. Results: Mean total cholesterol was 202, HDL 50, LDL 121, triglycerides 157 and non-HDL cholesterol 152 mg/dl. Total/HDL cholesterol ratio was 4.3. Mean IMT was 0.62 mm. All lipid markers were significantly correlated with IMT This correlation was higher for non-HDL cholesterol (r = 0.24, p < 0.0001) and total/HDL cholesterol ratio(r = 0.23, p < 0.0001). In both men and women, total/HDL cholesterol ratio was the best predictor of having an IMT over the 75th percentile (odds ratio 1.21, 95% confidence intervals 1.09-1.35, p < 0.01). Conclusions: Total/HDL cholesterol ratio was the best determinant of subclinical atherosclerosis. (Rev Med Chile 2012; 140: 969-976).
dc.fechaingreso.objetodigital2024-05-28
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0034-98872012000800001
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:23282768
dc.identifier.urihttps://doi.org/10.4067/S0034-98872012000800001
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78812
dc.identifier.wosidWOS:000309152000001
dc.information.autorucMedicina;Acevedo M;S/I;81173
dc.information.autorucMedicina;Arnaiz P;S/I;98982
dc.information.autorucMedicina;Berrios X;S/I;98139
dc.information.autorucMedicina;Corbalan R;S/I;98700
dc.information.autorucMedicina;Kramer V;S/I;4946
dc.information.autorucMedicina;Tagle R;S/I;59867
dc.issue.numero8
dc.language.isoit
dc.nota.accesoContenido completo
dc.pagina.final976
dc.pagina.inicio969
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsacceso abierto
dc.subjectCarotid intimae-media thickness
dc.subjectCholesterol
dc.subjectRisk factors
dc.subjectDENSITY LIPOPROTEIN CHOLESTEROL
dc.subjectCARDIOVASCULAR-DISEASE
dc.subjectHEART-DISEASE
dc.subjectRISK-FACTORS
dc.subjectA-I
dc.subjectCORONARY
dc.subjectAPOLIPOPROTEINS
dc.subjectATHEROSCLEROSIS
dc.subjectPREVENTION
dc.subjectEVENTS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleTotal/HDL cholesterol ratio and non HDL cholesterol as predictors for increased intima media thickness
dc.typeartículo
dc.volumen140
sipa.codpersvinculados81173
sipa.codpersvinculados98982
sipa.codpersvinculados98139
sipa.codpersvinculados98700
sipa.codpersvinculados4946
sipa.codpersvinculados59867
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Total-HDL cholesterol ratio and non HDL cholesterol as predictors for increased intima media thickness.pdf
Size:
5.77 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas