Performance of the cerebral state index during increasing levels of propofol anesthesia: A comparison with the bispectral index

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dc.contributor.authorCortinez, Luis I.
dc.contributor.authorDelfino, Alejandro E.
dc.contributor.authorFuentes, Ricardo
dc.contributor.authorMunoz, Hernan R.
dc.date.accessioned2024-01-10T12:07:27Z
dc.date.available2024-01-10T12:07:27Z
dc.date.issued2007
dc.description.abstractBACKGROUND: The cerebral state monitor is a new device to measure depth of anesthesia. In this study we compared the cerebral state monitor with the bispectral index (BIS) monitor during propofol anesthesia.
dc.description.abstractMETHODS: Fifteen healthy patients received a continuous infusion of propofol (300 mL/h). The cerebral state index (CSI) and the BIS values were recorded until burst suppression ratio >= 60%. Baseline variability, prediction probability, and agreement analysis between indices were evaluated. Clinical markers of loss of consciousness were also assessed.
dc.description.abstractRESULTS: Mean awake BIS and CSI values were 95.6 and 91.6, respectively (P = 0.01). BIS and CSI prediction probability values (mean +/- SD) were estimated to be 0.87 +/- 0.08 and 0.86 +/- 0.08, respectively (NS). The CSI tended to stabilize at values of 60-40 when estimated propofol concentrations at the effect site increased from 5 to 8 mu g/mL. The BIS stabilized at values of 40-20 when the propofol concentrations at the effect site increased from 7 to 10 mu g/mL. The mean BIS-CSI difference was -7.4 with 95% limits of agreement of 22.2 and -36.9. The BlS and CSI correlation with the burst suppression ratio was -0.60 and -0.97, respectively (P < 0.01). Predicted BIS and CSI values for loss of eyelash reflex in 50% and 95% of the patients were different (P < 0.05).
dc.description.abstractCONCLUSION: The overall performance of both monitors during propofol induction was similar. However, the different dynamic profiles of these monitors indicate that BIS may be a more useful index for evaluating intermediate anesthetic levels, whereas CSI may be better for evaluating deeper anesthetic levels.
dc.fechaingreso.objetodigital2024-05-15
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1213/01.ane.0000255152.96354.17
dc.identifier.issn0003-2999
dc.identifier.pubmedidMEDLINE:17312217
dc.identifier.urihttps://doi.org/10.1213/01.ane.0000255152.96354.17
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76285
dc.identifier.wosidWOS:000244431500032
dc.information.autorucMedicina;Muñoz H;S/I;73573
dc.issue.numero3
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final610
dc.pagina.inicio605
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.revistaANESTHESIA AND ANALGESIA
dc.rightsacceso restringido
dc.subjectEVOKED POTENTIAL INDEX
dc.subjectCLINICAL END-POINTS
dc.subjectEFFECT-SITE EC50
dc.subjectDEPTH
dc.titlePerformance of the cerebral state index during increasing levels of propofol anesthesia: A comparison with the bispectral index
dc.typeartículo
dc.volumen104
sipa.codpersvinculados73573
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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