Dexamethasone for postoperative nausea and vomiting prophylaxis: effect on glycaemia in obese patients with impaired glucose tolerance

dc.contributor.authorNazar, Claudio E.
dc.contributor.authorLacassie, Hector J.
dc.contributor.authorLopez, Rodrigo A.
dc.contributor.authorMunoz, Hernan R.
dc.date.accessioned2024-01-10T12:04:54Z
dc.date.available2024-01-10T12:04:54Z
dc.date.issued2009
dc.description.abstractBackground and objective Dexamethasone given to prevent postoperative nausea and vomiting may produce significant hyperglycaemia in the perioperative period. effect of dexamethasone on patients with impaired tolerance is unknown.
dc.description.abstractMethods Thirty obese patients with impaired glucose tolerance undergoing laparoscopic Roux-en-Y gastric bypass surgery were studied in a double-blind fashion. Patients were randomly distributed into two groups: the dexamethasone group (n =15) received dexamethasone 8 mg intravenously after induction of anaesthesia; the control group (n =15) received isotonic saline. capillary blood glucose concentrations were measured at baseline and every 2 h during the first 12 h after the start surgery.
dc.description.abstractResults In both groups, all blood glucose concentrations measured after the beginning of surgery were higher baseline values. However, the dexamethasone group showed higher glucose concentrations than the control group from the 6th to the 12th hour of the study. In addition, the maximum blood glucose value in the dexamethasone group (10.4 +/- 1.6 mmol l(-1)) was higher than in the controls (8.8 +/- 1.7 mmol l(-1)) (P<0.05).
dc.description.abstractConclusion Dexamethasone, 8 mg, intravenously administered at the beginning of laparoscopic bariatric surgery in patients with impaired glucose tolerance is associated with significantly increased postoperative blood glucose concentrations. Eur J Anaesthesiol 26:318-321 (c) 2009 European Society of Anaesthesiology.
dc.fechaingreso.objetodigital2024-05-22
dc.format.extent4 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1097/EJA.0b013e328319c09b
dc.identifier.eissn1365-2346
dc.identifier.issn0265-0215
dc.identifier.pubmedidMEDLINE:19401661
dc.identifier.urihttps://doi.org/10.1097/EJA.0b013e328319c09b
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75906
dc.identifier.wosidWOS:000264716700009
dc.information.autorucMedicina;Lacassie HJ;S/I;68956
dc.information.autorucMedicina;Lopez RA;S/I;15192
dc.information.autorucMedicina;Muñoz HR;S/I;73573
dc.information.autorucMedicina;Nazar CE;S/I;129215
dc.issue.numero4
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final321
dc.pagina.inicio318
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.revistaEUROPEAN JOURNAL OF ANAESTHESIOLOGY
dc.rightsacceso restringido
dc.subjectbariatric surgery
dc.subjectcomplications
dc.subjectpostoperative nausea and vomiting
dc.subjectpostoperative period prophylaxis
dc.subjectHYPERGLYCEMIA
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDexamethasone for postoperative nausea and vomiting prophylaxis: effect on glycaemia in obese patients with impaired glucose tolerance
dc.typeartículo
dc.volumen26
sipa.codpersvinculados68956
sipa.codpersvinculados15192
sipa.codpersvinculados73573
sipa.codpersvinculados129215
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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