Study of the contribution of nicotinic receptors to the release of endogenous biogenic amines in Drosophila brain

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dc.catalogadoraba
dc.contributor.authorFuenzalida-Uribe, N.
dc.contributor.authorHidalgo, S.
dc.contributor.authorVaras, R.
dc.contributor.authorCampusano, J.M.
dc.date.accessioned2024-03-04T15:19:37Z
dc.date.available2024-03-04T15:19:37Z
dc.date.issued2016
dc.description.abstractBiogenic amines (BAs) are a group of molecules that act as neurotransmitters or neuromodulators in key regions of the brain involved in the development and consolidation of behaviors. The deregulation of neural systems containing and releasing BAs has been linked to several neurologic diseases. To understand the signals that modulate aminergic systems in the brain is essential in advancing our comprehension on the contribution of these bioactive molecules to brain normal functioning and pathological events. In our laboratory we use the fly Drosophila melanogaster, an animal model that shows similar mechanisms of neurotransmitter storage, release, and recycling as compared to mammalian systems but with powerful genetic tools, to elucidate the contribution of nicotinic ligands to the regulation of aminergic signaling in the brain. In this chapter we comment on some methodological approaches to tackle this issue, with special emphasis on one of the techniques used in our laboratory, chronoamperometry
dc.fechaingreso.objetodigital2024-02-26
dc.format.extent12 páginas
dc.fuente.origenORCID
dc.identifier.doi10.1007/978-1-4939-3768-4_4
dc.identifier.eisbn978-1-4939-3768-4
dc.identifier.eissn1940-6045
dc.identifier.isbn978-1-4939-3766-0
dc.identifier.issn0893-2336
dc.identifier.urihttps://doi.org/10.1007/978-1-4939-3768-4_4
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/82430
dc.language.isoen
dc.lugar.publicacionNew York
dc.nota.accesoContenido parcial
dc.pagina.final76
dc.pagina.inicio65
dc.publisherHumana Press
dc.rightsacceso restringido
dc.subjectNicotinic receptors
dc.subjectBiogenic amines release
dc.subjectChronoamperometry
dc.subjectDrosophila
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleStudy of the contribution of nicotinic receptors to the release of endogenous biogenic amines in Drosophila brain
dc.typelibro
sipa.codpersvinculados3965
sipa.trazabilidadORCID;2024-01-15
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