From scrophula to mycobacterial lymphadenitis

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dc.contributor.authorDuarte, Ignacio
dc.date.accessioned2024-01-10T12:05:36Z
dc.date.available2024-01-10T12:05:36Z
dc.date.issued2017
dc.description.abstractIn the 19th century it was widely believed that both tuberculosis and cervical lymph node swelling, known as scrophula, affected individuals predisposed to an inherited "diathetic constitution". In 1882 Robert Koch proved that human tuberculosis and scrophulous lesions were caused by the bacillus Mycobacterium tuberculosis. In the early twentieth century it was stated that Mycobacterium bovis, the bacillus of cattle tuberculosis, could also cause cervical lymphoadenitis in humans, especially in children, by the intake of milk from sick cows. The incidence of this condition decreased after the infection was controlled in cattle and pasteurization of the milk was introduced. A type of granulomatous necrotizing and suppurative cervico-facial lymphadenitis associated to non-tuberculous mycobacteria was described in 1956. It mainly affects children younger than 5 years old, particularly those born in countries with non-endemic tuberculosis. Tuberculous cervical lymphadenitis is prevalent in young adults from tuberculosis-endemic countries and in HIV-infected subjects. Infectious etiology displaced the importance of a personal disposition in the development of scrophula. Nevertheless, mutations that confer susceptibility to mycobacterial infection are currently investigated.
dc.fechaingreso.objetodigital2024-06-25
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6341
dc.identifier.issn0716-1018
dc.identifier.pubmedidMEDLINE:29488555
dc.identifier.urihttp://dx.doi.org/10.4067/S0716-10182017000600589
dc.identifier.wosidWOS:000423254200013
dc.information.autorucMedicina;Duarte I ;S/I;98528
dc.issue.numero6
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final595
dc.pagina.inicio589
dc.publisherSOC CHILENA INFECTOLOGIA
dc.revistaREVISTA CHILENA DE INFECTOLOGIA
dc.rightsacceso abierto
dc.subjectScrophula
dc.subjectlymphadenitis
dc.subjecttuberculosis
dc.subjectmycobacteria
dc.subjectcattle
dc.subjectpasteurization
dc.subjectPERIPHERAL TUBERCULOUS LYMPHADENITIS
dc.subjectCERVICAL LYMPHADENOPATHY
dc.subjectBACTERIOLOGICAL SURVEY
dc.subjectSOUTHEAST ENGLAND
dc.subjectINFECTION
dc.subjectDIAGNOSIS
dc.subjectADENITIS
dc.subjectDISEASES
dc.subjectCHILDREN
dc.subjectSUSCEPTIBILITY
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleFrom scrophula to mycobacterial lymphadenitis
dc.typeartículo
dc.volumen34
sipa.codpersvinculados98528
sipa.indexWOS
sipa.indexScielo
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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