Assessment and Impact of Cognitive Impairment in Multiple Sclerosis : an Overview

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dc.catalogadorgrr
dc.contributor.authorMacías I., M.
dc.contributor.authorCiampi Diaz, Ethel Leslie
dc.date.accessioned2024-01-16T15:08:05Z
dc.date.available2024-01-16T15:08:05Z
dc.date.issued2019
dc.description.abstractCognitive impairment affects 40-60% of patients with multiple sclerosis. It may be present early in the course of the disease and has an impact on a patient's employability, social interactions, and quality of life. In the last three decades, an increasing interest in diagnosis and management of cognitive impairment has arisen. Neuropsychological assessment and neuroimaging studies focusing on cognitive impairment are now being incorporated as primary outcomes in clinical trials. However, there are still key uncertainties concerning the underlying mechanisms of damage, neural basis, sensitivity and validity of neuropsychological tests, and efficacy of pharmacological and non-pharmacological interventions. The present article aimed to present an overview of the assessment, neural correlates, and impact of cognitive impairment in multiple sclerosis.
dc.fechaingreso.objetodigital2024-01-16
dc.format.extent19 páginas
dc.fuente.origenORCID-ene24
dc.identifier.doi10.3390/biomedicines7010022
dc.identifier.eissn2227-9059
dc.identifier.issn2227-9059
dc.identifier.pubmedid30893874
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80481
dc.identifier.wosidWOS:000464224000002
dc.information.autorucEscuela de Medicina; Ciampi Diaz, Ethel Leslie; 0000-0002-7330-5433; 132794
dc.issue.numero1
dc.language.isoen
dc.nota.accesoContenido completo
dc.revistaBiomedicines
dc.rightsacceso abierto
dc.rights.licenseAtribución 4.0 Internacional (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectMultiple sclerosis
dc.subjectDemyelinating diseases
dc.subjectCognitive impairment
dc.subjectCognitive dysfunction
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAssessment and Impact of Cognitive Impairment in Multiple Sclerosis : an Overview
dc.typeartículo
dc.volumen7
sipa.codpersvinculados132794
sipa.trazabilidadORCID;2024-01-15
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