Case report: psoriasis relapse following adrenalectomy for cushing syndrome

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dc.catalogadoraba
dc.contributor.authorAchurra Tirado, Pablo
dc.contributor.authorEugenin Soto, María Ignacia
dc.contributor.authorOrlandini Sánchez, Elisa Javiera
dc.contributor.authorSoto, Nestor
dc.contributor.authorGarcía-huidobro Munita, Diego Nicolás
dc.date.accessioned2024-06-10T21:25:29Z
dc.date.available2024-06-10T21:25:29Z
dc.date.issued2011
dc.description.abstractThe relapse of autoimmune diseases following resolution of Cushing syndrome (CS) has been established with frequency, especially for thyroid disease. We present the case of a 39-year-old woman with a history of psoriasis vulgaris, with no other comorbidities. She presented a one-year of weight gain, high blood pressure, hypermenorrhea, pre-diabetes and dyslipidemia. During this period of time, the complete remission of psoriatic lesions was confirmed. The laboratory analysis demonstrated elevated free urinary cortisol in two opportunities, and a confirmatory low-dose dexamethasone test. Low ACTH levels were established (12,3pg/ml), and the abdominal images where compatible with a right adrenal adenoma of 3,0 x 2,3 cm, so the patient underwent a laparoscopic right adrenalectomy with no complications. Her blood pressure, glucose and cholesterol levels improved following surgery. One month after surgery the patient developed new, generalized psoriatic plaques. The excess of glucocorticoids produced by the adrenal tumor could have controlled the immunopathogeny of psoriasis. By removing the tumor, with the consequent reduction of cortisol levels, a more severe relapse of her cutaneous disease occurred.
dc.fuente.origenORCID
dc.identifier.eissn0719-5400
dc.identifier.issn0718-493x
dc.identifier.urihttp://www.revistasoched.cl/1_2012/6.html
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/86690
dc.information.autorucEscuela de Medicina; Achurra Tirado, Pablo; 0000-0001-6803-423X; 156236
dc.information.autorucEscuela de Medicina; Eugenin Soto, María Ignacia; S/I; 157940
dc.information.autorucEscuela de Medicina; Orlandini Sánchez, Elisa Javiera; 0000-0002-6582-7733; 169858
dc.information.autorucEscuela de Medicina; García-huidobro Munita, Diego Nicolás; 0000-0003-1964-7640; 16671
dc.issue.numero1
dc.language.isoes
dc.revistaRevista Chilena de Endocrinología y Diabetes
dc.rightsacceso restringido
dc.subjectPsoriasis
dc.subjectCushing syndrome
dc.subjectAdrenalectomy
dc.subjectRecurrence
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleCase report: psoriasis relapse following adrenalectomy for cushing syndrome
dc.typeartículo
dc.volumen5
sipa.codpersvinculados156236
sipa.codpersvinculados157940
sipa.codpersvinculados169858
sipa.codpersvinculados16671
sipa.trazabilidadORCID;2024-06-03
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