Binding and production of insulin-like growth factor-I in rat mammary gland
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Date
1991
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Abstract
1. Mammary tissue from pregnant rat presents low and high affinity IGF-I functional receptors.
2. Mammary explants from pregnant and lactating rats secrete IGF-I and its production was related to the developmental stage of the gland.
3. An inverse relationship between IGF-I production and tissue binding capacity was observed.