Persistent Symptoms of Dengue: Estimates of the Incremental Disease and Economic Burden in Mexico

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dc.catalogadorpau
dc.contributor.authorCarolina Tiga, D.
dc.contributor.authorUndurraga Fourcade, Eduardo Andrés
dc.contributor.authorRamos-Castaneda, Jose
dc.contributor.authorMartinez-Vega, Ruth
dc.contributor.authorHalasa, Yara A.
dc.contributor.authorShepard, Donald S.
dc.date.accessioned2023-07-21T17:46:06Z
dc.date.available2023-07-21T17:46:06Z
dc.date.issued2015
dc.description.abstractDengue is mostly considered an acute illness with three phases: febrile, critical with possible hemorrhagic manifestations, and recovery. But some patients present persistent symptoms, including fatigue and depression, as acknowledged by the World Health Organization. If persistent symptoms affect a non-negligible share of patients, the burden of dengue will be underestimated. On the basis of a systematic literature review and econometric modeling, we found a significant relationship between the share of patients reporting persisting symptoms and time. We updated estimates of the economic burden of dengue in Mexico, addressing uncertainty in productivity loss and incremental expenses using Monte Carlo simulations. Persistent symptoms represent annually about US$22.6 (95% certainty level [CL]: US$13–US$29) million in incremental costs and 28.2 (95% CL: 21.6–36.2) additional disability-adjusted life years per million population, or 13% and 43% increases over previous estimates, respectively. Although our estimates have uncertainty from limited data, they show a substantial, unmeasured burden. Similar patterns likely extend to other dengue-endemic countries.
dc.fechaingreso.objetodigital2015-10-01
dc.format.extent1 página
dc.fuente.origenORCID
dc.identifier.doi10.4269/ajtmh.15-0896
dc.identifier.issn0002-9637
dc.identifier.urihttp://dx.doi.org/10.4269/ajtmh.15-0896
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856607/
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/74238
dc.information.autorucEscuela de Gobierno; Undurraga Fourcade, Eduardo Andrés; 0000-0002-4425-1253; 12868
dc.issue.numero5
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final435
dc.pagina.inicio435
dc.revistaThe American Journal of Tropical Medicine and Hygienees_ES
dc.rightsacceso restringido
dc.titlePersistent Symptoms of Dengue: Estimates of the Incremental Disease and Economic Burden in Mexicoes_ES
dc.typeartículo
dc.volumen93
sipa.codpersvinculados12868
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