Stereology of the Human Thyroid Gland

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dc.contributor.authorGuillermo Salgado, A.
dc.contributor.authorVasquez, Belgica
dc.contributor.authordel Sol, Mariano
dc.date.accessioned2024-01-10T12:08:49Z
dc.date.available2024-01-10T12:08:49Z
dc.date.issued2011
dc.description.abstractThe thyroid gland is a an extensive, medium and symmetrical endocrine gland situated on the anterior side of the neck at the lower third and the upper third junction. The thyroid follicle is the functional and structural unit of the thyroid gland. Follicles are separated from each other by narrow interfollicular connective tissue. Stereo logical values of follicular, parafollicular and colloid containing follicles have been observed in experimental animal models. The aim of this study was to determine the existence of a stereological pattern in the human thyroid gland defined by age and sex. A sample of six human thyroid glands of adult males with no history of thyroid disease or disorder obtained from non fixed human cadavers; of these cadavers the gland was removed and processed for thyroid follicle density (21.09 mm(2)/mm(3)), follicular cell number density (10.81 x 10(5) cells/mm(3)) and parafollicular (1.81 x 10 cells/mm(3)). With the average gland volume (21.3 mm(3)) we determined the total number of follicular cells (230.22 x 10(5)) and parafollicular (38.33 x 10(5)). The number of follicles per mm (2) (46.18 follicles/mm(2)) was also determined. Prior information and knowledge of numerical values and normal stereological proportions provides excellent parameters for determining hyper or hypotrophic endemic or exogenous alterations leading to stratification of certain disorders which was already observed in experimental models where differences amongst models were significant.
dc.fechaingreso.objetodigital2024-07-09
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0717-95022011000200044
dc.identifier.issn0717-9502
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76430
dc.identifier.wosidWOS:000293661000044
dc.information.autorucMedicina;Salgado G ;S/I;1008579
dc.issue.numero2
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final567
dc.pagina.inicio562
dc.publisherSOC CHILENA ANATOMIA
dc.revistaINTERNATIONAL JOURNAL OF MORPHOLOGY
dc.rightsacceso abierto
dc.subjectThyroid gland
dc.subjectMorphology
dc.subjectStereology
dc.subjectRATS
dc.subjectFRACTIONATOR
dc.subjectEXPOSURE
dc.subjectVOLUME
dc.subjectCELLS
dc.subject.ods03 Good Health and Well-being
dc.subject.ods05 Gender Equality
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa05 Igualdad de género
dc.titleStereology of the Human Thyroid Gland
dc.typeartículo
dc.volumen29
sipa.codpersvinculados1008579
sipa.indexWOS
sipa.indexScielo
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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