Intra-abdominal hypertension: Incidence and association with organ dysfunction during early septic shock

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dc.contributor.authorRegueira, Tomas
dc.contributor.authorBruhn, Alejandro
dc.contributor.authorHasbun, Pablo
dc.contributor.authorAguirre, Marcia
dc.contributor.authorRomero, Carlos
dc.contributor.authorLlanos, Osvaldo
dc.contributor.authorCastro, Ricardo
dc.contributor.authorBugedo, Guillermo
dc.contributor.authorHernandez, Glenn
dc.date.accessioned2024-01-10T13:14:04Z
dc.date.available2024-01-10T13:14:04Z
dc.date.issued2008
dc.description.abstractPurpose: The objective of this article is to study the cumulative incidence of intra-abdominal hypertension (IAH) in septic shock (SS) patients during the first 72 hours of intensive care unit (ICU) admission and to determine if the presence and severity of IAH are associated with sepsis morbidity and mortality.
dc.description.abstractMaterials and Methods: Eighty-one consecutive SS patients admitted to a surgical-medical ICU of an academic university hospital (January 2005 to January 2006) were included. Intra-abdominal pressure (IAP) and abdominal perfusion pressure (AAP) were measured every 6 h (intermittently) for 72 h. Intra-abdominal pressure was registered as minimal, mean, and maximal values per day, during shock and throughout the study period. Intra-abdominal hypertension was diagnosed if IAP remained 12 mm Hg or throughout the study period. Intra-abdominal hypertension was diagnosed if IAP remained 12 mm Hg or higher on 2 consecutive measurements and stratified according to the most recent consensus definition (www.wsacs.org).
dc.description.abstractResults: According to maximal and mean IAP values, 67 (82.7%) and 62 (76.5%) of the patients developed IAH during the study period, respectively. Mean IAP values remained stable throughout the Study Period. Surgical patients had a higher incidence of IAH than medical patients (93% vs 73%, P < .009). Maximal IAPs were normally distributed, with nonsurvivors exhibiting significantly higher IAP levels during shock (survivors, 17.2 +/- 5.3 nonsurvivors. 19.9 +/- 5.6 mm Hg; P <.04). Patients with IAH exhibited significantly lower values of APP and diuresis, higher values of lactate and creatinine, and higher maximal norepinephrine doses, and were more frequently mechanically ventilated (P <.05 for all). Increasing degrees of IAH and the development of the abdominal compartment syndrome were associated with lower APP and higher maximal serum creatinine levels (P <.03 for both).
dc.description.abstractConclusions: Septic shock patients have a very high incidence of IAH, which seems to be associated with the severity of shock and could be related to the development of organ dysfunctions, particularly renal dysfunction. Intra-abdominal pressure Should be routinely monitored during the course of SS. (c) 2008 Elsevier Inc. All rights reserved.
dc.fechaingreso.objetodigital27-03-2024
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.jcrc.2007.12.013
dc.identifier.eissn1557-8615
dc.identifier.issn0883-9441
dc.identifier.pubmedidMEDLINE:19056007
dc.identifier.urihttps://doi.org/10.1016/j.jcrc.2007.12.013
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78369
dc.identifier.wosidWOS:000261747500005
dc.information.autorucMedicina;Aguirre M;S/I;152804
dc.information.autorucMedicina;Bruhn A;S/I;741
dc.information.autorucMedicina;Bugedo G;S/I;60490
dc.information.autorucMedicina;Castro R;S/I;4537
dc.information.autorucMedicina;Hasbún P;S/I;135610
dc.information.autorucMedicina;Hernández G;S/I;98874
dc.information.autorucMedicina;Llanos O;S/I;98426
dc.information.autorucMedicina;Regueira T;S/I;18434
dc.information.autorucMedicina;Romero C;S/I;1001942
dc.issue.numero4
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final467
dc.pagina.inicio461
dc.publisherW B SAUNDERS CO-ELSEVIER INC
dc.revistaJOURNAL OF CRITICAL CARE
dc.rightsacceso restringido
dc.subjectIntra-abdominal hypertension
dc.subjectSeptic shock
dc.subjectAbdominal perfusion pressure
dc.subjectABDOMINAL COMPARTMENT SYNDROME
dc.subjectCRITICALLY-ILL PATIENTS
dc.subjectRENAL-FUNCTION
dc.subjectINTERNATIONAL-CONFERENCE
dc.subjectLIVER-TRANSPLANTATION
dc.subjectLUNG INJURY
dc.subjectPRESSURE
dc.subjectTRAUMA
dc.subjectLAPAROTOMY
dc.subjectMANAGEMENT
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleIntra-abdominal hypertension: Incidence and association with organ dysfunction during early septic shock
dc.typeartículo
dc.volumen23
sipa.codpersvinculados152804
sipa.codpersvinculados741
sipa.codpersvinculados60490
sipa.codpersvinculados4537
sipa.codpersvinculados135610
sipa.codpersvinculados98874
sipa.codpersvinculados98426
sipa.codpersvinculados18434
sipa.codpersvinculados1001942
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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