Monitoring Changes in Oxygen Muscle during Exercise with High-Flow Nasal Cannula Using Wearable NIRS Biosensors

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dc.article.number985
dc.catalogadorgjm
dc.contributor.authorContreras Briceño, Felipe
dc.contributor.authorEspinosa Ramírez, Maximiliano
dc.contributor.authorRivera Greene, Augusta
dc.contributor.authorGuerra Venegas, Camila Isidora
dc.contributor.authorLungenstrass Poulsen, Antonia Isabel
dc.contributor.authorVillagra Reyes, Victoria Paz
dc.contributor.authorCaulier Cisterna, Raúl
dc.contributor.authorAraneda, Oscar F.
dc.contributor.authorViscor, Ginés
dc.date.accessioned2023-11-23T13:38:22Z
dc.date.available2023-11-23T13:38:22Z
dc.date.issued2023
dc.description.abstractExercise increases the cost of breathing (COB) due to increased lung ventilation (V˙ E), inducing respiratory muscles deoxygenation (∇ SmO2), while the increase in workload implies ∇ SmO2 in locomotor muscles. This phenomenon has been proposed as a leading cause of exercise intolerance, especially in clinical contexts. The use of high-flow nasal cannula (HFNC) during exercise routines in rehabilitation programs has gained significant interest because it is proposed as a therapeutic intervention for reducing symptoms associated with exercise intolerance, such as fatigue and dyspnea, assuming that HFNC could reduce exercise-induced ∇ SmO2. SmO2 can be detected using optical wearable devices provided by near-infrared spectroscopy (NIRS) technology, which measures the changes in the amount of oxygen bound to chromophores (e.g., hemoglobin, myoglobin, cytochrome oxidase) at the target tissue level. We tested in a study with a cross-over design whether the muscular desaturation of m.vastus lateralis and m.intercostales during a high-intensity constant-load exercise can be reduced when it was supported with HFNC in non-physically active adults. Eighteen participants (nine women; age: 22 ± 2 years, weight: 65.1 ± 11.2 kg, height: 173.0 ± 5.8 cm, BMI: 21.6 ± 2.8 kg·m−2) were evaluated in a cycle ergometer (15 min, 70% maximum watts achieved in ergospirometry (V˙ O2-peak)) breathing spontaneously (control, CTRL) or with HFNC support (HFNC; 50 L·min−1, fiO2: 21%, 30 °C), separated by seven days in randomized order. Two-way ANOVA tests analyzed the ∇ SmO2 (m.intercostales and m.vastus lateralis), and changes in V˙ E and ∇ SmO2·V˙ E−1. Dyspnea, leg fatigue, and effort level (RPE) were compared between trials by the Wilcoxon matched-paired signed rank test. We found that the interaction of factors (trial × exercise-time) was significant in ∇ SmO2-m.intercostales, V˙ E, and (∇ SmO2-m.intercostales)/V˙ E (p < 0.05, all) but not in ∇ SmO2-m.vastus lateralis. ∇ SmO2-m.intercostales was more pronounced in CTRL during exercise since 5′ (p < 0.05). Hyperventilation was higher in CTRL since 10′ (p < 0.05). The ∇ SmO2·V˙ E−1 decreased during exercise, being lowest in CTRL since 5′. Lower dyspnea was reported in HFNC, with no differences in leg fatigue and RPE. We concluded that wearable optical biosensors documented the beneficial effect of HFNC in COB due to lower respiratory ∇ SmO2 induced by exercise. We suggest incorporating NIRS devices in rehabilitation programs to monitor physiological changes that can support the clinical impact of the therapeutic intervention implemented.
dc.fechaingreso.objetodigital2023-11-23
dc.format.extent17 páginas
dc.fuente.origenORCID
dc.identifier.doi10.3390/bios13110985
dc.identifier.urihttps://doi.org/10.3390/bios13110985
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75404
dc.information.autorucDepartamento de Ciencias de la Salud; Contreras Briceño, Felipe; 0000-0002-0674-7506; 1011730
dc.information.autorucDepartamento de Ciencias de la Salud; Espinosa Ramírez, Maximiliano; S/I; 215830
dc.information.autorucDepartamento de Ciencias de la Salud; Rivera Greene, Augusta; S/I; 1089405
dc.information.autorucDepartamento de Ciencias de la Salud; Guerra Venegas, Camila Isidora; S/I; 1089424
dc.information.autorucDepartamento de Ciencias de la Salud; Lungenstrass Poulsen, Antonia Isabel; S/I; 1089404
dc.information.autorucDepartamento de Ciencias de la Salud; Villagra Reyes, Victoria Paz; S/I; 1047588
dc.issue.numero11
dc.language.isoen
dc.nota.accesoContenido completo
dc.revistaBiosensors
dc.rightsacceso abierto
dc.subjectNear-infrared spectroscopy
dc.subjectExercise
dc.subjectRehabilitation
dc.subjectWearable
dc.subjectOptical
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMonitoring Changes in Oxygen Muscle during Exercise with High-Flow Nasal Cannula Using Wearable NIRS Biosensors
dc.typeartículo
dc.volumen13
sipa.codpersvinculados1011730
sipa.codpersvinculados215830
sipa.codpersvinculados1089405
sipa.codpersvinculados1089424
sipa.codpersvinculados1089404
sipa.codpersvinculados1047588
sipa.trazabilidadORCID;2023-11-20
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