Obesity and gynecological cancers: A toxic relationship

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dc.contributor.authorWichmann, Ignacio A.
dc.contributor.authorCuello, Mauricio A.
dc.date.accessioned2024-01-10T13:10:19Z
dc.date.available2024-01-10T13:10:19Z
dc.date.issued2021
dc.description.abstractDespite the evidence supporting the relevance of obesity and obesity-associated disorders in the development, management, and prognosis of various cancers, obesity rates continue to increase worldwide. Growing evidence supports the involvement of obesity in the development of gynecologic malignancies. This article explores the molecular basis governing the alteration of hallmarks of cancer in the development of obesity-related gynecologic malignancies encompassing cervical, endometrial, and ovarian cancers. We highlight specific examples of how development, management, and prognosis are affected for each cancer, incorporate current knowledge on complementary approaches including lifestyle interventions to improve patient outcomes, and highlight how new technologies are helping us better understand the biology underlying this neglected pandemic.
dc.fechaingreso.objetodigital05-04-2024
dc.format.extent12 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1002/ijgo.13870
dc.identifier.eissn1879-3479
dc.identifier.issn0020-7292
dc.identifier.pubmedidMEDLINE:34669205
dc.identifier.urihttps://doi.org/10.1002/ijgo.13870
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77835
dc.identifier.wosidWOS:000709008900013
dc.information.autorucFacultad de Medicina; Wichmann Pérez, Ignacio Alberto; S/I; 149908
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final134
dc.pagina.inicio123
dc.publisherWILEY
dc.revistaINTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
dc.rightsacceso abierto
dc.subjectcarcinogenesis
dc.subjectendometrial neoplasms
dc.subjectFIGO Cancer Report
dc.subjectobesity
dc.subjectovarian neoplasms
dc.subjectprognoses
dc.subjecttreatment outcome
dc.subjectuterine cervix neoplasms
dc.subjectBODY-MASS INDEX
dc.subjectSEROUS OVARIAN-CANCER
dc.subjectMETABOLIC SYNDROME
dc.subjectENDOMETRIAL CANCER
dc.subjectRISK
dc.subjectSURVIVAL
dc.subjectIMPACT
dc.subjectWOMEN
dc.subjectASSOCIATION
dc.subjectMANAGEMENT
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleObesity and gynecological cancers: A toxic relationship
dc.typeartículo
dc.volumen155
sipa.codpersvinculados149908
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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