New spirometric reference equations for healthy Chilean adults

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dc.contributor.authorGutierrez C, Monica
dc.contributor.authorValdivia C, Gonzalo
dc.contributor.authorVillarroel D, Luis
dc.contributor.authorContreras T, Gustavo
dc.contributor.authorCartagena S, Claudia
dc.contributor.authorLisboa B, Carmen
dc.date.accessioned2024-01-10T13:44:30Z
dc.date.available2024-01-10T13:44:30Z
dc.date.issued2014
dc.description.abstractBackground: To correctly interpret spirometric results, reference values should come from the same population. Current spirometric reference equations have been under scrutiny due to deficiencies to fit adequately for Chilean population, specially, for those aged over 65 years old. Aim: To develop new spiro metric reference values for Chilean adults, based on national studies in which spirometries were performed in healthy non-smoker adults. Material and Methods: A standardized database of spirometric values was developed combining spirometric data collected from five population-based studies, in which healthy nonsmoker adults participated. Spirometries from 448 males aged 19 to 84 years and from 726 females aged 19 to 94 years, obtained according to guidelines from the American Thoracic and European Respiratory Societies, were analyzed. Using multiple regression models, which included height, gender, and age, the theoretical value and inferior limits of normality were calculated for 1st second (FEV1), forced vital capacity (PVC), FEV1/FVC, and forced mid-expiratory flow rate (FEF25-75). Results: Reference values and lower limits of normality (LLN) were constructed for Chilean adults of both genders. The new proposed set of equations had a better fit, when compared with the current reference values used in Chile. Conclusions: The new spirometric references values derived from this study, fit better than currently used ones. Therefore, they should be used as new references values for Chilean adults.
dc.fechaingreso.objetodigital2024-05-29
dc.format.extent10 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0034-98872014000200001
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:24953101
dc.identifier.urihttps://doi.org/10.4067/S0034-98872014000200001
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78901
dc.identifier.wosidWOS:000334816600001
dc.information.autorucFacultad de Medicina; Valdivia Cabrera, Gonzalo Sergio; S/I; 57007
dc.issue.numero2
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final152
dc.pagina.inicio143
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsacceso abierto
dc.subjectReference values
dc.subjectRespiratory function tests
dc.subjectSpirometry
dc.subjectLATIN-AMERICAN CITIES
dc.subjectBODY-MASS INDEX
dc.subjectLUNG-FUNCTION
dc.subjectREFERENCE VALUES
dc.subjectPULMONARY-FUNCTION
dc.subjectFEV1/FVC RATIO
dc.subjectLOWER LIMIT
dc.subjectCAPACITY
dc.subjectDISEASE
dc.subjectSAMPLE
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleNew spirometric reference equations for healthy Chilean adults
dc.typeartículo
dc.volumen142
sipa.codpersvinculados57007
sipa.indexWOS
sipa.indexPubmed
sipa.trazabilidadCarga SIPA;09-01-2024
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