Cardiac dyssynchrony correlates with left ventricular remodeling after myocardial infarctionLa disincronía cardíaca se correlaciona con el remodelado ventricular izquierdo postinfarto agudo al miocardio

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dc.contributor.authorMcNab P.
dc.contributor.authorCastro P.
dc.contributor.authorGabrielli L.
dc.contributor.authorVerdejo H.
dc.contributor.authorQuintana J.
dc.contributor.authorRodríguez J.
dc.contributor.authorCorbalán R.
dc.date.accessioned2024-01-10T14:22:53Z
dc.date.available2024-01-10T14:22:53Z
dc.date.issued2009
dc.description.abstractBackground: Cardiac dyssynchrony is common in advanced heart failure (HF), but the changes in cardiac synchrony after myocardial infarction (MI) have not been adequately described. Aim: To study the relationship between cardiac synchrony and left ventricular remodeling after acute myocardial infarction. Material and methods: Forty nine patients aged 59±10 years (77% men) with a first episode of a ST segment elevation MI, were studied. Scintigraphic left ventricular function and synchrony analyses were performed at baseline and after a six months follow-up. Determinations were compared with 33 healthy subjects. Results: At baseline, patients with MI had a decreased left ventricular ejection fraction (LVEF) and significant dyssynchrony, when compared with controls. LVEF was 36.4%±10%, left ventricular end-diastolic volume (LVEDV) 127±38 mL, interventricular delay (IEV) 29±35 miliseconds (ms), and intraventricular delay (IAV), 234±89 ms. After 6 months, LVEF significantly improved (38%±10%, p =0.042) without significant changes in LVEDV (129±32 mL, p =0.97), IEV (24±17, p =0.96) or IAV (231±97, p =0.34). At baseline there were significant correlations between IAV and LVEF, and between IAV and LVEDV (r =-0.48, p =0.001 and r =-0.41, p =0.004, respectively). These correlations remained significant after 6 months. There was a positive correlation between IAV and LVEDV changes at six months (r =0.403, p =0.04). Conclusions: The development of cardiac dyssynchrony correlates with adverse left ventricular remodeling after MI.
dc.fechaingreso.objetodigital2024-05-02
dc.fuente.origenScopus
dc.identifier.eissn07176163
dc.identifier.issn00349887 07176163
dc.identifier.pubmedid20098804
dc.identifier.scopusidSCOPUS_ID:72249110309
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80010
dc.information.autorucFacultad de Medicina; Verdejo Pinochet, Hugo Eduardo; S/I; 1001175
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final1462
dc.pagina.inicio1457
dc.revistaRevista Medica de Chile
dc.rightsregistro bibliográfico
dc.subjectCardiac dyssynchrony
dc.subjectMyocardial infarction
dc.subjectVentricular remodeling
dc.titleCardiac dyssynchrony correlates with left ventricular remodeling after myocardial infarctionLa disincronía cardíaca se correlaciona con el remodelado ventricular izquierdo postinfarto agudo al miocardio
dc.typeartículo
dc.volumen137
sipa.codpersvinculados1001175
sipa.indexScopus
sipa.indexPubmed
sipa.trazabilidadCarga SIPA;09-01-2024
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