ANTICARDIOLIPIN ANTIBODIES IN ACUTE RHEUMATIC-FEVER

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dc.contributor.authorFIGUEROA, F
dc.contributor.authorBERRIOS, X
dc.contributor.authorGUTIERREZ, M
dc.contributor.authorCARRION, F
dc.contributor.authorGOYCOLEA, JP
dc.contributor.authorRIEDEL, I
dc.contributor.authorJACOBELLI, S
dc.date.accessioned2024-01-10T12:04:15Z
dc.date.available2024-01-10T12:04:15Z
dc.date.issued1992
dc.description.abstractRecent reports describe the association of antiphospholipid antibodies (aPL) with chorea or severe heart valve lesions in systemic lupus erythematosus, lupus-like disease, or the primary antiphospholipid antibody syndrome. We conducted a case series and a case-control investigation of patients with rheumatic fever with Sydenham chorea or other manifestations of rheumatic fever for anticardiolipin antibodies (aCL) during the acute attack and disease remission. Eighty percent of patients were positive for aCL during the rheumatic fever attack vs 40% when inactive (p = 0.035); IgG and IgM aCL increased significantly with disease activity. Individuals with or without Sydenham chorea were equally positive for aCL (76 and 83%, respectively). A significant association was found between IgM aCL and carditis: All patients with valvulitis had IgM aCL (100%) vs 37% of patients without valvular involvement (p = 0.02). aPL may play a role in the pathogenesis of some clinical manifestations of acute rheumatic fever.
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.eissn1499-2752
dc.identifier.issn0315-162X
dc.identifier.pubmedidMEDLINE:1365552
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75739
dc.identifier.wosidWOS:A1992JH64200005
dc.information.autorucMedicina;Berrios X;S/I;98139
dc.information.autorucMedicina;Iacobelli S;S/I;98345
dc.issue.numero8
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final1180
dc.pagina.inicio1175
dc.publisherJ RHEUMATOL PUBL CO
dc.revistaJOURNAL OF RHEUMATOLOGY
dc.rightsregistro bibliográfico
dc.subjectRHEUMATIC FEVER
dc.subjectRHEUMATIC HEART DISEASE
dc.subjectSYDENHAM CHOREA
dc.subjectANTIPHOSPHOLIPID ANTICARDIOLIPIN ANTIBODIES
dc.subjectSYSTEMIC LUPUS-ERYTHEMATOSUS
dc.subjectVALVULAR HEART-DISEASE
dc.subjectSTREPTOCOCCAL-M-PROTEIN
dc.subjectANTIPHOSPHOLIPID ANTIBODIES
dc.subjectCARDIAC ABNORMALITIES
dc.subjectANTICOAGULANT
dc.subjectASSOCIATION
dc.subjectCHOREA
dc.subjectENDOCARDITIS
dc.subjectCARDIOLIPIN
dc.subject.ods03 Good Health and Well-being
dc.subject.ods05 Gender Equality
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa05 Igualdad de género
dc.titleANTICARDIOLIPIN ANTIBODIES IN ACUTE RHEUMATIC-FEVER
dc.typeartículo
dc.volumen19
sipa.codpersvinculados98139
sipa.codpersvinculados98345
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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