Prevalencia de sepsis grave en las Unidades de Cuidado Intensivo. Primer estudio nacional multicéntrico

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dc.catalogadorpau
dc.contributor.authorDougnac Labatut, Alberto
dc.contributor.authorMercado Flores, Marcelo Esteban
dc.contributor.authorCornejo Rosas, Rodrigo Alfredo
dc.contributor.authorCariaga Vergara, Mario Alberto
dc.contributor.authorHernández P., Glenn
dc.contributor.authorAndresen Hernández, Max Alfonso
dc.contributor.authorBugedo Tarraza, Guillermo
dc.contributor.authorCastillo Fuenzalida, Luis Benito
dc.date.accessioned2023-07-21T17:46:10Z
dc.date.available2023-07-21T17:46:10Z
dc.date.issued2007
dc.description.abstractBackground: Severe sepsis (SS) is the leading cause of death in the Intensive Care Units (ICU). Aim: To study the prevalence of SS in Chilean ICUs. Material and methods: An observational, cross-sectional study using a predesigned written survey was done in all ICUs of Chile on April 21st, 2004. General hospital and ICU data and the number of hospitalized patients in the hospital and in the ICU at the survey day, were recorded. Patients were followed for 28 days. Results: Ninety four percent of ICUs participated in the survey. The ICU occupation index was 66%. Mean age of patients was 57.7+18 years and 59% were male, APACHE II score was 15+7.5 and SOFA score was 6+4. SS was the admission diagnosis of 94 of the 283 patients (33%) and 38 patients presented SS after admission. On the survey day, 112 patients fulfilled SS criteria (40%). APACHE II and SOFA scores were significantly higher in SS patients than in non SS patients. Global case-fatality ratio at 28 days was 15.9% (45/283). Case-fatality ratio in patients with or without SS at the moment of the survey was 26.7% (30/112) and 8.7% (17/171), respectively p <0.05. Thirteen percent of patients who developed SS after admission, died. Case-fatality ratios for patients with SS from Santiago and the other cities were similar, but APACHE II score was significantly higher in patients from Santiago. In SS patients, the independent predictors of mortality were SS as cause of hospital admission, APACHE II and SOFA scores. Ninety nine percent of SS patients had a known sepsis focus (48% respiratory and 30% abdominal). Eighty five patients that presented SS after admission, had a respiratory focus. Conclusions: SS is highly prevalent in Chilean ICUs and represents the leading diagnosis at admission. SS as cause of hospitalization, APA CHE II and SOFA scores were independent predictors of mortality.
dc.fechaingreso.objetodigital2023-07-21
dc.format.extent11 páginas
dc.fuente.origenORCID
dc.identifier.issn0034-9887
dc.identifier.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-34347340672&partnerID=MN8TOARS
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/74253
dc.information.autorucEscuela de Medicina; Dougnac Labatut, Alberto; S/I; 54554
dc.information.autorucEscuela de Medicina; Mercado Flores, Marcelo Esteban; 0000-0001-7479-8076; 18889
dc.information.autorucEscuela de Medicina; Cornejo Rosas, Rodrigo Alfredo; 0000-0002-0497-5740; 146070
dc.information.autorucEscuela de Medicina; Cariaga Vergara, Mario Alberto; S/I; 2465
dc.information.autorucEscuela de Medicina; Hernández P., Glenn; S/I; 98874
dc.information.autorucEscuela de Medicina; Andresen Hernández, Max Alfonso; S/I; 0000-0003-1874-1416; 54274
dc.information.autorucEscuela de Medicina; Bugedo Tarraza, Guillermo; 0000-0001-7527-6202; 60490
dc.information.autorucEscuela de Medicina; Castillo Fuenzalida, Luis Benito; S/I; 54397
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final630
dc.pagina.inicio620
dc.revistaRevista médica de Chilees_ES
dc.rightsacceso abierto
dc.subjectFatal outcome
dc.subjectIntensive care units
dc.subjectSepsis
dc.titlePrevalencia de sepsis grave en las Unidades de Cuidado Intensivo. Primer estudio nacional multicéntricoes_ES
dc.title.alternativePrevalence of severe sepsis in Intensive Care Units. A national multicentric studyes_ES
dc.typeartículo
dc.volumen135
sipa.codpersvinculados54554
sipa.codpersvinculados18889
sipa.codpersvinculados146070
sipa.codpersvinculados2465
sipa.codpersvinculados98874
sipa.codpersvinculados54274
sipa.codpersvinculados60490
sipa.codpersvinculados54397
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