Risk-stratified Results among Congenital Diaphragmatic Hernia Patients in Two Large Extracorporeal Membrane Oxygenation Centers in South America

Simple item page
dc.catalogadorjca
dc.contributor.authorLuco Illanes, Matías
dc.contributor.authorSalas, Gisela
dc.contributor.authorZavala Busquets, Alejandro Luis
dc.contributor.authorOtano, Jesica
dc.contributor.authorToso Milos, Alberto
dc.contributor.authorReusmann, Aixa
dc.contributor.authorCannizzaro, Claudia
dc.contributor.authorSantelices Ruiz, Felipe
dc.contributor.authorFarina, Diana
dc.contributor.authorLally, Pam
dc.contributor.authorKattan Said, Alberto
dc.date.accessioned2023-12-04T19:45:19Z
dc.date.available2023-12-04T19:45:19Z
dc.date.issued2023
dc.description.abstractIntroduction: Mortality related to CDH is high, but with great variability among centers. There are few studies on patients with this condition born in South America which show poor outcomes. The goal of this study is to present the outcome of CDH in several high-volume quaternary centers in South America, ascertain the factors associated with lower mortality in our population, and compare our outcomes to those of the CDH Study Group (CDHSG).Methods: The data from two South American centers were retrospectively analyzed and compared with contemporary data from other CDHSG participating centers. Patient demographic and clinical characteristics were also evaluated and compared.Results: Between 2013 and 2018, the two South American centers saw 335 patients with CDH with an overall survival rate of 73.1%. Survival for the high, intermediate, and low-risk groups as determined by the Brindle score was 50%, 70%, and 87%, respectively. In our cohort the strongest predictors of mortality were ECMO use and early PaCO2. There were no significant differences in mortality between the two South American centers and the other CDHSG centers when adjusted by risk score, however, the South American centers had higher use of ECMO in the intermediate-risk group.Discussion: Quaternary South American centers had similar outcomes to CDHSG centers worldwide. The availability and coordination of centralized dedicated care allow more efficient use of scarce technical and professional resources in patients with CDH. Level of evidence: III.& COPY; 2023 Elsevier Inc. All rights reserved.
dc.fechaingreso.objetodigital2023-12-04
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.jpedsurg.2023.01.058
dc.identifier.eissn1531-5037
dc.identifier.issn0022-3468
dc.identifier.urihttps://doi.org/10.1016/j.jpedsurg.2023.01.058
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75467
dc.identifier.wosidWOS:001034263600001
dc.information.autorucEscuela de Medicina; Luco Illanes, Matías; 0000-0002-7698-8065; 7023
dc.information.autorucEscuela de Medicina; Toso Milos, Alberto; 0000-0002-3809-2567; 238020
dc.information.autorucEscuela de Medicina; Santelices Ruiz, Felipe; S/I; 209536
dc.information.autorucEscuela de Medicina; Kattan Said, Alberto Javier; 0000-0002-2911-5982; 53324
dc.information.autorucEscuela de Medicina; Zavala Busquets, Alejandro Luis; S/I; 100099
dc.issue.numero7
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final1234
dc.pagina.inicio1230
dc.publisherW B SAUNDERS CO-ELSEVIER INC
dc.revistaJournal of Pediatric Surgery
dc.rightsacceso restringido
dc.subjectCongenital diaphragmatic hernia
dc.subjectECMO
dc.subjectECLS
dc.subjectCDH
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRisk-stratified Results among Congenital Diaphragmatic Hernia Patients in Two Large Extracorporeal Membrane Oxygenation Centers in South America
dc.typeartículo
dc.volumen58
sipa.codpersvinculados7023
sipa.codpersvinculados238020
sipa.codpersvinculados209536
sipa.codpersvinculados53324
sipa.codpersvinculados100099
sipa.trazabilidadORCID;2023-12-04
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
4-12.pdf
Size:
109.24 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas