Gills de novo assembly reveals oxidative stress, unfolded protein, and immune response on red cusk-eel (<i> Genypterus</i> chilensis ) under thermal stress

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dc.contributor.authorDettleff, Phillip
dc.contributor.authorToloza, Carla
dc.contributor.authorFuentes, Marcia
dc.contributor.authorAedo, Jorge
dc.contributor.authorZuloaga, Rodrigo
dc.contributor.authorEstrada, Juan Manuel
dc.contributor.authorMolina, Alfredo
dc.contributor.authorValdes, Juan Antonio
dc.date.accessioned2025-01-20T16:18:06Z
dc.date.available2025-01-20T16:18:06Z
dc.date.issued2024
dc.description.abstractThe heat waves on the South Pacific coast could lead to thermal stress in native fish. The red cusk-eel ( Genypterus chilensis ) is relevant for Chilean artisanal fisheries and aquaculture diversification. This study examined the effect of high-temperature stress in the gills of G. chilensis in control (14 degrees C) and high-temperature stress (19 degrees C) conditions. High-temperature stress induces a significant increase in gills cortisol levels. Additionally, oxidative damage was observed in gills (protein carbonylation and lipoperoxidation). RNA-seq data was used to build the first transcriptome assembly of gills in this species (23,656 annotated transcripts). A total of 1138 downregulated and 1531 up-regulated transcripts were observed in response to high-temperature stress in gills. The enrichment analysis showed immune response and replication enriched processes (on down-regulated transcripts), and processes related to the folding of proteins, endoplasmic reticulum, and transporter activity (on upregulated transcripts). The present study showed how gills could be affected by high-temperature stress.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.marenvres.2024.106440
dc.identifier.eissn1879-0291
dc.identifier.issn0141-1136
dc.identifier.urihttps://doi.org/10.1016/j.marenvres.2024.106440
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/90631
dc.identifier.wosidWOS:001220998900001
dc.language.isoen
dc.revistaMarine environmental research
dc.rightsacceso restringido
dc.subjectRNA-seq
dc.subjectHigh temperature
dc.subjectTeleost
dc.subjectHeat waves
dc.subjectOxidative damage
dc.subjectGene expression
dc.subject.ods14 Life below water
dc.subject.odspa14 Vida submarina
dc.titleGills de novo assembly reveals oxidative stress, unfolded protein, and immune response on red cusk-eel (<i> Genypterus</i> chilensis ) under thermal stress
dc.typeartículo
dc.volumen196
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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