Arsenic exposure from drinking water and birth weight

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dc.contributor.authorHopenhayn, C
dc.contributor.authorFerreccio, C
dc.contributor.authorBrowning, SR
dc.contributor.authorHuang, B
dc.contributor.authorPeralta, C
dc.contributor.authorGibb, H
dc.contributor.authorHertz Picciotto, I
dc.date.accessioned2024-01-10T13:46:04Z
dc.date.available2024-01-10T13:46:04Z
dc.date.issued2003
dc.description.abstractBackground: Arsenic exposures front drinking water increase the risk of various cancers and noncancer health endpoints. Limited evidence suggests that arsenic may have adverse human reproductive effects. We investigated the association between drinking water arsenic exposure and fetal growth, as manifest in birth weight.
dc.description.abstractMethods: We conducted a prospective cohort study in two Chilean cities with contrasting drinking water arsenic levels: Antofagasta (40 mug/L) and Valparaiso (<1 &mu;g/L). Study subjects completed in-depth interviews and provided urine samples for exposure analysis. We obtained pregnancy and birth information from medical records. The birth weight analysis was restricted to liveborn, singleton infants born between December 1998 and February 2000.
dc.description.abstractResults: The final study group consisted of 424 infants from Antofagasta and 420 from Valparaiso. After controlling for confounders, results of the multivariable analysis indicated that Antofagasta infants had lower mean birth weight (-57 g; 95% confidence interval = -123 to 9).
dc.description.abstractConclusion: This study suggests that moderate arsenic exposures from drinking water (<50 mug/L) during pregnancy are associated with reduction in birth weight, similar in magnitude to that resulting from other environmental exposures such as environmental tobacco smoke and benzene.
dc.fechaingreso.objetodigital2024-05-02
dc.format.extent10 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1097/01.ede.0000072104.65240.69
dc.identifier.issn1044-3983
dc.identifier.pubmedidMEDLINE:14501275
dc.identifier.urihttps://doi.org/10.1097/01.ede.0000072104.65240.69
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79116
dc.identifier.wosidWOS:000185132900014
dc.information.autorucMedicina;Ferreccio F;S/I;99684
dc.issue.numero5
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final602
dc.pagina.inicio593
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.revistaEPIDEMIOLOGY
dc.rightsacceso restringido
dc.subjectarsenic
dc.subjectdrinking water
dc.subjectreproductive effects
dc.subjectenvironmental exposure
dc.subjectbirth weight
dc.subjectENVIRONMENTAL RISKS
dc.subjectDEPRESSIVE SYMPTOMS
dc.subjectNORTHERN SWEDEN
dc.subjectSPONTANEOUS-ABORTION
dc.subjectPREGNANCY OUTCOMES
dc.subjectDIABETES-MELLITUS
dc.subjectCANCER-MORTALITY
dc.subjectVASCULAR-DISEASE
dc.subjectLIPID PEROXIDES
dc.subjectYOUNG-CHILDREN
dc.subject.ods03 Good Health and Well-being
dc.subject.ods06 Clean Water and Sanitation
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa06 Agua limpia y saneamiento
dc.titleArsenic exposure from drinking water and birth weight
dc.typeartículo
dc.volumen14
sipa.codpersvinculados99684
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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