PET/MRI of atherosclerosis

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dc.catalogadorgjm
dc.contributor.authorAizaz, Mueez
dc.contributor.authorMoonen, Rik P.M.
dc.contributor.authorPol, Jochem A.J. van der
dc.contributor.authorPrieto Vásquez, Claudia
dc.contributor.authorBotnar, René Michael
dc.contributor.authorKooi, M. Eline
dc.date.accessioned2023-05-19T20:50:52Z
dc.date.available2023-05-19T20:50:52Z
dc.date.issued2020
dc.description.abstractMyocardial infarction and stroke are the most prevalent global causes of death. Each year 15 million people worldwide die due to myocardial infarction or stroke. Rupture of a vulnerable atherosclerotic plaque is the main underlying cause of stroke and myocardial infarction. Key features of a vulnerable plaque are inflammation, a large lipid-rich necrotic core (LRNC) with a thin or ruptured overlying fibrous cap, and intraplaque hemorrhage (IPH). Noninvasive imaging of these features could have a role in risk stratification of myocardial infarction and stroke and can potentially be utilized for treatment guidance and monitoring. The recent development of hybrid PET/MRI combining the superior soft tissue contrast of MRI with the opportunity to visualize specific plaque features using various radioactive tracers, paves the way for comprehensive plaque imaging. In this review, the use of hybrid PET/MRI for atherosclerotic plaque imaging in carotid and coronary arteries is discussed. The pros and cons of different hybrid PET/MRI systems arc reviewed. The challenges in the development of PET/MRI and potential solutions are described. An overview of PET and MRI acquisition techniques for imaging of atherosclerosis including motion correction is provided, followed by a summary of vessel wall imaging PET/MRI studies in patients with carotid and coronary artery disease. Finally, the future of imaging of atherosclerosis with PET/MRI is discussed.
dc.fechaingreso.objetodigital2023-07-14
dc.fuente.origenORCID
dc.identifier.doi10.21037/cdt.2020.02.09
dc.identifier.eissn2223-3660
dc.identifier.issn2223-3652
dc.identifier.pubmedidPMID: 32968664
dc.identifier.urihttp://doi.org/10.21037/cdt.2
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/70366
dc.information.autorucEscuela de Ingeniería; Prieto Vásquez, Claudia; 0000-0003-4602-2523; 14195
dc.information.autorucEscuela de Ingeniería; Botnar, René Michael; 0000-0002-9447-4367; 1015313
dc.issue.numero4
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final1139
dc.pagina.inicio1120
dc.revistaCardiovascular Diagnosis and Therapy
dc.rightsacceso abierto
dc.subjectAtherosclerosises_ES
dc.subjectHybrid imaginges_ES
dc.subjectPET/MRIes_ES
dc.subjectVasculares_ES
dc.subjectVulnerable plaquees_ES
dc.subject.ddc620
dc.subject.deweyIngenieríaes_ES
dc.titlePET/MRI of atherosclerosises_ES
dc.typeartículo
dc.volumen10
sipa.codpersvinculados14195
sipa.codpersvinculados1015313
sipa.indexPubmed
sipa.trazabilidadORCID;14-07-2023
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