Physiological and inflammatory consequences of high and low respiratory rate in acute respiratory distress syndrome

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dc.contributor.authorRetamal J.
dc.contributor.authorDamiani L.F.
dc.contributor.authorBasoalto R.
dc.contributor.authorBruhn A.
dc.contributor.authorBugedo G.
dc.contributor.authorDamiani L.F.
dc.contributor.authorBenites M.H.
dc.contributor.authorLarsson A.
dc.date.accessioned2024-01-10T14:23:33Z
dc.date.available2024-01-10T14:23:33Z
dc.date.issued2021
dc.description.abstract© 2021 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons LtdUsing protective mechanical ventilation strategies with low tidal volume is usually accompanied by an increment of respiratory rate to maintain adequate alveolar ventilation. However, there is no robust data that support the safety of a high respiratory rate concerning ventilator-induced lung injury. Several experimental animal studies have explored the effects of respiratory rate over lung physiology, using a wide range of frequencies and different models. Clinical evidence is scarce and restricted to the physiological impact of increased respiratory rate. Undoubtedly, the respiratory rate can influence respiratory mechanics in various ways as a factor of multiplication of the power of ventilation, and gas exchange, and also on alveolar dynamics. In this narrative review, we present our point of view over the main experimental and clinical evidence available regarding the effect of respiratory rate on ventilator-induced lung injury development.
dc.fechaingreso.objetodigital2024-05-14
dc.fuente.origenScopus
dc.identifier.doi10.1111/aas.13830
dc.identifier.eissn13996576
dc.identifier.issn13996576 00015172
dc.identifier.pubmedid33844272
dc.identifier.scopusidSCOPUS_ID:85105236875
dc.identifier.urihttps://doi.org/10.1111/aas.13830
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80111
dc.identifier.wosidWOS:000645954500001
dc.information.autorucFacultad de Medicina; Damiani Rebolledo, Luis Felipe; S/I; 237645
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final1022
dc.pagina.inicio1013
dc.publisherJohn Wiley and Sons Inc
dc.revistaActa Anaesthesiologica Scandinavica
dc.rightsregistro bibliográfico
dc.subjectacute respiratory distress syndrome
dc.subjectrespiratory rate
dc.subjectventilator-induced lung injury
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePhysiological and inflammatory consequences of high and low respiratory rate in acute respiratory distress syndrome
dc.typeartículo de revisión
dc.volumen65
sipa.codpersvinculados237645
sipa.indexWos
sipa.indexScopus
sipa.indexPubmed
sipa.trazabilidadCarga SIPA;09-01-2024
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