Pathological characteristics of thyroid microcarcinoma. A review of 402 biopsies

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dc.contributor.authorFardella, C
dc.contributor.authorJimenez, M
dc.contributor.authorGonzalez, H
dc.contributor.authorLeon, A
dc.contributor.authorGoni, I
dc.contributor.authorCruz, F
dc.contributor.authorSolar, A
dc.contributor.authorTorres, J
dc.contributor.authorMosso, L
dc.contributor.authorGonzalez, G
dc.contributor.authorRodriguez, JA
dc.contributor.authorCampusano, C
dc.contributor.authorLopez, JM
dc.contributor.authorArteaga, E
dc.date.accessioned2024-08-15T08:00:07Z
dc.date.available2024-08-15T08:00:07Z
dc.date.issued2005
dc.description.abstractBackground: Thyroid microcarcinoma is a tumor of 10 mm or less. that should have a low risk of mortality. However a subgroup of these carcinomas is as aggressive as bigger tumors. Aim To describe the pathological presentation of these tumors.. and compare them with larger tumors. Material and methods. All Pathological samples of thyroid carcinoma that were obtained between 1992 and 2003, were studied. In all biopsies, the pathological type, tumor size. the focal or multifocal character the presence of lymph node involvement and the presence of lymphocytic thyroiditis or thyroid hyperplasia, were recorded. Results: One hundred eighteen microcarcinomas and 284 larger tumors were studied. The mean age of patients with microcarcinoma and larger tumors was 42.7 +/- 14 and 49.3 +/- 16 years respectively (p < 0,00.1) and 83% were female. without gender differences between tumor types. klean size of microcarcinomas was 8.6 mm and 116 (98%) were papillary carcinomas. Of these. 109 (94% were well differentiated and seven (6%) were moderatly differentiated. Thirty six(31%) were multifocal and in 10 (8,6%), there was lymph node involvement. The mean size of larger tumors was 23.8 mm and 241 (85%) were papillary carcinomas. Of these, 200 (83%) were well differentiated, and 41 (17%) were moderately differentiated.Eighty five (35%) were multifocal and in 44 (18%) there was lymph node involvement. The prevalence of thyroiditis and hyperplasia was significantly higher among microcardinomas than in larger tumors (15 and 2.5%, respectively, p < 0.001, for the former; 32.4 and 1.7%, respectively, p < 0.001, for the latter. Conclusions. In this series. one third of microcarcinomas were multifocal and 10% had lymph node involvement. Therefore, aggresiveness of these tumors is higher than what is reported in the literature and they should be treated with total thyroidectomy.
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:16446853
dc.identifier.scopusidSCOPUS_ID:0033155140
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/87443
dc.identifier.wosidWOS:000234699300005
dc.information.autorucFacultad de Medicina; Mosso Gomez, Lorena Montserrat; S/I; 88201
dc.issue.numero11
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final1310
dc.pagina.inicio1305
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsregistro bibliográfico
dc.subjectneoplasms
dc.subjectglandular and epithelial
dc.subjectthyroid neoplasms
dc.subjectthyroidectomy
dc.subjectLYMPH-NODE METASTASIS
dc.subjectPAPILLARY
dc.subjectRECURRENCE
dc.subjectNODULES
dc.subjectTUMORS
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePathological characteristics of thyroid microcarcinoma. A review of 402 biopsies
dc.typeartículo
dc.volumen133
sipa.codpersvinculados88201
sipa.indexWOS
sipa.indexPubmed
sipa.trazabilidadCarga WOS-SCOPUS;15-08-2024
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