Prevalence of components of the metabolic syndrome according to birthweight among overweight and obese children and adolescents

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dc.contributor.authorEyzaguirre, Francisca
dc.contributor.authorBancalari, Rodrigo
dc.contributor.authorRoman, Rossana
dc.contributor.authorSilva, Ricardo
dc.contributor.authorYoulton, Ronald
dc.contributor.authorUrquidi, Cinthyia
dc.contributor.authorGarcia, Hernan
dc.contributor.authorMericq, Veronica
dc.date.accessioned2024-01-10T12:41:43Z
dc.date.available2024-01-10T12:41:43Z
dc.date.issued2012
dc.description.abstractBackground/objectives: Extremes of birthweight (BW) have been associated with increased rates of metabolic risks. The objective was to study the prevalence of metabolic risks markers among obese and overweight (OW) subjects according to BW.
dc.description.abstractSubjects/methods: A cross-sectional study was performed in a cohort of 1002 patients (2-18 years, 40.6% male) evaluated for OW or obese subjects in two private clinics. Anthropometrics, fasting lipids, glycemia, and insulin were obtained.
dc.description.abstractResults: Of the subjects, 76.1% were born appropriate for gestational age (AGA), 10.9% small for gestational age (SGA), and 13% large for gestational age (LGA). Children born LGA presented a more severe degree of obesity compared with those born AGA and SGA (p < 0.0001). No differences in glycemia, insulin, and lipid levels were detected among the groups. Abnormal glucose was found in 37 subjects: one with type 2 diabetes mellitus (from the previously glucose-intolerant subjects), 10 with glucose intolerance, and 27 with impaired fasting glucose. According to Boney criteria, 6.6% of the patients (6-18 years old) exhibited metabolic syndrome (MS) (69.4% AGA, 12.9% SGA, and 17.7% LGA).
dc.description.abstractConclusions: Being born LGA represents a higher risk of severe obesity. At this age, the most frequent component of MS was an abnormal lipid profile with low high-density lipoprotein and high triglycerides. Finally, the most frequent finding associated with abnormalities of glucose tolerance was a family history of diabetes. Thus, BW, lipid profile, and family history are mandatory when these patients are evaluated.
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1515/JPEM.2011.446
dc.identifier.eissn2191-0251
dc.identifier.issn0334-018X
dc.identifier.pubmedidMEDLINE:22570950
dc.identifier.urihttps://doi.org/10.1515/JPEM.2011.446
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77444
dc.identifier.wosidWOS:000305708000007
dc.information.autorucMedicina;Garcia H;S/I;1006495
dc.issue.numero1-2
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final56
dc.pagina.inicio51
dc.publisherWALTER DE GRUYTER GMBH
dc.revistaJOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
dc.rightsregistro bibliográfico
dc.subjectmetabolic syndrome
dc.subjectsmall and large for gestational age
dc.subjectCARDIOVASCULAR RISK-FACTORS
dc.subjectIMPAIRED GLUCOSE-TOLERANCE
dc.subject3RD NATIONAL-HEALTH
dc.subjectINSULIN-RESISTANCE
dc.subjectFASTING GLUCOSE
dc.subjectASSOCIATION
dc.subjectADIPOSITY
dc.subjectADULTHOOD
dc.subjectCHILDHOOD
dc.subjectSURROGATE
dc.subject.ods03 Good Health and Well-being
dc.subject.ods05 Gender Equality
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa05 Igualdad de género
dc.titlePrevalence of components of the metabolic syndrome according to birthweight among overweight and obese children and adolescents
dc.typeartículo
dc.volumen25
sipa.codpersvinculados1006495
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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