Genome-wide analysis in response to nitrogen and carbon identifies regulators for root AtNRT2 transporters

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dc.catalogadorjlo
dc.contributor.authorRuffel, Sandrine
dc.contributor.authorChaput, Valentín
dc.contributor.authorPrzybyla Toscano, Jonathan
dc.contributor.authorFayos, Ian
dc.contributor.authorIbarra, Catalina
dc.contributor.authorMoyano, Tomás
dc.contributor.authorFizames, Cécile
dc.contributor.authorTillard, Pascal
dc.contributor.authorO’Brien, José Antonio
dc.contributor.authorGutiérrez, Rodrigo A.
dc.contributor.authorGojon, Alain
dc.contributor.authorLejay, Laurence
dc.date.accessioned2024-01-29T17:48:30Z
dc.date.available2024-01-29T17:48:30Z
dc.date.issued2021
dc.description.abstractIn Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (⁠NO3−⁠) uptake depends mainly on four NRT2 NO3− transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. The HATS is the target of many regulations to coordinate nitrogen (N) acquisition with the N status of the plant and with carbon (C) assimilation through photosynthesis. At the molecular level, C and N signaling pathways control gene expression of the NRT2 transporters. Although several regulators of these transporters have been identified in response to either N or C signals, the response of NRT2 gene expression to the interaction of these signals has never been specifically investigated, and the underlying molecular mechanisms remain largely unknown. To address this question we used an original systems biology approach to model a regulatory gene network targeting NRT2.1, NRT2.2, NRT2.4, and NRT2.5 in response to N/C signals. Our systems analysis of the data identified three transcription factors, TGA3, MYC1, and bHLH093. Functional analysis of mutants combined with yeast one-hybrid experiments confirmed that all three transcription factors are regulators of NRT2.4 or NRT2.5 in response to N or C signals. These results reveal a role for TGA3, MYC1, and bHLH093 in controlling the expression of root NRT2 transporter genes.
dc.fuente.origenORCID-ene24
dc.identifier.doi10.1093/plphys/kiab047
dc.identifier.issn0032-0889
dc.identifier.urihttps://doi.org/10.1093/plphys/kiab047
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/81024
dc.information.autorucFacultad de Ciencias Biológicas; O'brien Opazo, José Antonio Ramiro; 0000-0002-1788-1786; 237767
dc.issue.numero1
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final714
dc.pagina.inicio696
dc.revistaPlant Physiology
dc.rightsacceso restringido
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleGenome-wide analysis in response to nitrogen and carbon identifies regulators for root AtNRT2 transporters
dc.typeartículo
dc.volumen186
sipa.codpersvinculados237767
sipa.trazabilidadORCID;2024-01-15
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