Subject-specific tribo-contact conditions in total knee replacements: a simulation framework across scales

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dc.catalogadorjca
dc.contributor.authorRothammer, Benedict
dc.contributor.authorWolf, Alexander
dc.contributor.authorWinkler, Andreas
dc.contributor.authorSchulte-Hubbert, Felix
dc.contributor.authorBartz, Marcel
dc.contributor.authorWartzack, Sandro
dc.contributor.authorMiehling, Jörg
dc.contributor.authorMarian, Max
dc.date.accessioned2024-06-06T14:28:10Z
dc.date.available2024-06-06T14:28:10Z
dc.date.issued2023
dc.description.abstractFundamental knowledge about in vivo kinematics and contact conditions at the articulating interfaces of total knee replacements are essential for predicting and optimizing their behavior and durability. However, the prevailing motions and contact stresses in total knee replacements cannot be precisely determined using conventional in vivo measurement methods. In silico modeling, in turn, allows for a prediction of the loads, velocities, deformations, stress, and lubrication conditions across the scales during gait. Within the scope of this paper, we therefore combine musculoskeletal modeling with tribo-contact modeling. In the first step, we compute contact forces and sliding velocities by means of inverse dynamics approach and force-dependent kinematic solver based upon experimental gait data, revealing contact forces during healthy/physiological gait of young subjects. In a second step, the derived data are employed as input data for an elastohydrodynamic model based upon the finite element method full-system approach taking into account elastic deformation, the synovial fluid’s hydrodynamics as well as mixed lubrication to predict and discuss the subject-specific pressure and lubrication conditions.
dc.fuente.origenORCID
dc.identifier.doi10.1007/s10237-023-01726-1
dc.identifier.urihttps://doi.org/10.1007/s10237-023-01726-1
dc.identifier.urihttps://link.springer.com/article/10.1007/s10237-023-01726-1
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/86514
dc.information.autorucEscuela de Ingeniería; Marian , Max; 0000-0003-2045-6649; 1247429
dc.language.isoen
dc.nota.accesocontenido completo
dc.pagina.final1410
dc.pagina.inicio1395
dc.revistaBiomechanics and Modeling in Mechanobiology
dc.rightsacceso abierto
dc.subjectTotal knee replacement
dc.subjectBiomechanics
dc.subjectBiotribology
dc.subjectMultiscale simulation
dc.subjectIn silico modeling
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleSubject-specific tribo-contact conditions in total knee replacements: a simulation framework across scales
dc.typeartículo
dc.volumen22
sipa.codpersvinculados1247429
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