Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy

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dc.contributor.authorDomingo, Carles
dc.contributor.authorLagares, Juan Ignacio
dc.contributor.authorRomero-Expósito, Maite
dc.contributor.authorSánchez Nieto, Beatriz
dc.contributor.authorNieto-Camero, Jaime J.
dc.contributor.authorTerrón, José Antonio
dc.contributor.authorIrazola, Leticia
dc.contributor.authorDasu, Alexandru
dc.contributor.authorSánchez-Doblado, Francisco
dc.date.accessioned2023-01-16T19:24:18Z
dc.date.available2023-01-16T19:24:18Z
dc.date.issued2022
dc.description.abstractThe aim of this work is to present a reproducible methodology for the evaluation of total equivalent doses in organs during proton therapy facilities. The methodology is based on measuring the dose equivalent in representative locations inside an anthropomorphic phantom where photon and neutron dosimeters were inserted. The Monte Carlo simulation was needed for obtaining neutron energy distribution inside the phantom. The methodology was implemented for a head irradiation case in the passive proton beam of iThemba Labs (South Africa). Thermoluminescent dosimeter (TLD)-600 and TLD-700 pairs were used as dosimeters inside the phantom and GEANT code for simulations. In addition, Bonner sphere spectrometry was performed inside the treatment room to obtain the neutron spectra, some relevant neutron dosimetric quantities per treatment Gy, and a percentual distribution of neutron fluence and ambient dose equivalent in four energy groups, at two locations. The neutron spectrum at one of those locations was also simulated so that a reasonable agreement between simulation and measurement allowed a validation of the simulation. Results showed that the total out-of-field dose equivalent inside the phantom ranged from 1.4 to 0.28 mSv/Gy, mainly due to the neutron contribution and with a small contribution from photons, 10% on average. The order of magnitude of the equivalent dose in organs was similar, displaying a slow reduction in values as the organ is farther from the target volume. These values were in agreement with those found by other authors in other passive beam facilities under similar irradiation and measurement conditions.
dc.fuente.origenWOS
dc.identifier.doi10.3389/fonc.2022.882476
dc.identifier.issn2234-943X
dc.identifier.urihttps://www.frontiersin.org/articles/10.3389/fonc.2022.882476/full
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/66352
dc.identifier.wosidWOS:000807813600001
dc.information.autorucInstituto de física ; Sánchez Nieto, Beatriz ; 0000-0003-0713-3108 ; 192291
dc.language.isoen
dc.nota.accesoContenido completo
dc.revistaFrontiers in Oncology
dc.rightsacceso abierto
dc.subjectPeripheral organ dose
dc.subjectProton therapy
dc.subjectNeutron spectrometry
dc.subjectSecondary cancer risk
dc.subjectNeutron and photon dose
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePeripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy
dc.typeartículo
dc.volumen12
sipa.codpersvinculados192291
sipa.indexWOS
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