Characteristics, management, and outcomes of illicit drug consumers with acute myocardial infarction

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dc.contributor.authorBartolucci, Jorge
dc.contributor.authorNazzal N, Carolina
dc.contributor.authorVerdugo, Fernando J.
dc.contributor.authorCarlos Prieto, Juan
dc.contributor.authorSepulveda, Pablo
dc.contributor.authorCorbalan, Ramon
dc.contributor.authorGEMI
dc.date.accessioned2024-01-10T12:37:56Z
dc.date.available2024-01-10T12:37:56Z
dc.date.issued2016
dc.description.abstractBackground: Consumption of illicit drugs (ID) has been associated with an increased risk of acute myocardial infarction (AMI). There is limited national evidence about the impact of substance use over the clinical presentation, management and outcomes of AMI patients. Aim: To describe the prevalence of ID consumption in patients within the Chilean Registry of Myocardial Infarction (GEMI), comparing clinical characteristics, management and outcome according to consumption status. Material and Methods: We reviewed data from the GEMI registry between 2001 and 2013, identifying 18,048 patients with AMI. The sample was stratified according to presence or absence of previous ID consumption, comparing different demographic and clinical variables between groups. Results: Two hundred eighty five patients (1.6%) had history of ID consumption (cocaine in 66%, cannabis in 35% and central nervous system stimulants in 24.0%). Compared with non-users, ID consumers were younger, predominantly male and had a lower prevalence of cardiovascular risk factors, except for tobacco smoking (86.3% and 42.5% respectively, p < 0.01). Among consumers, there was a higher percentage of ST segment elevation (85.2% and 67.8% respectively, p < 0.01) and anterior wall AMI (59.9 and 49.5% respectively, p = 0.01). Additionally, they had a higher rate of primary angioplasty (48.8% and 25.5% respectively, p < 0.01). There was no difference in hospital mortality between groups when stratified by age. Conclusions: A low percentage of patients with AMI had a previous history of ID consumption in our national setting. These patients were younger and had a greater frequency of ST segment elevation AMI, which probably determined a more invasive management.
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:26998981
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76954
dc.identifier.wosidWOS:000371280000006
dc.information.autorucMedicina; Corbalan R;S/I;98700
dc.information.autorucFacultad de Medicina; Sepulveda Varela, Pablo Andres; S/I; 1095919
dc.issue.numero1
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final46
dc.pagina.inicio39
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsregistro bibliográfico
dc.subjectCannabis
dc.subjectCocaine
dc.subjectHospital Mortality
dc.subjectMyocardial Infarction
dc.subjectStreet Drugs
dc.subjectNORMAL CORONARY-ARTERIES
dc.subjectCOCAINE USE
dc.subjectCHEST-PAIN
dc.subjectBETA-BLOCKERS
dc.subjectMARIJUANA USE
dc.subjectMORTALITY
dc.subjectRISK
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCharacteristics, management, and outcomes of illicit drug consumers with acute myocardial infarction
dc.typeartículo
dc.volumen144
sipa.codpersvinculados98700
sipa.codpersvinculados1095919
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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