M-CHAT-R/F Validation as a screening tool for early detection in children with autism spectrum disorder

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dc.contributor.authorElisa Coelho Mcdeiros, Maria
dc.contributor.authorBronstein, Jonathan
dc.contributor.authorAedo, Karim
dc.contributor.authorPereira, Jaime A.
dc.contributor.authorArrano, Veronica
dc.contributor.authorPerez, Carolina A.
dc.contributor.authorValenzuela, Patricia M.
dc.contributor.authorMoore, Rosario
dc.contributor.authorGarrido, Isabel
dc.contributor.authorBedregal, Paula
dc.date.accessioned2024-01-10T14:22:35Z
dc.date.available2024-01-10T14:22:35Z
dc.date.issued2019
dc.description.abstractIntroduction: Screening for Autism Spectrum Disorders (ASD) using the Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT-R/F) increases early detection, allowing early interventions and improving prognosis. This tool is part of the management in case of suspected ASD in several clinical guidelines. The objective of this article was to conduct the concurrent and discriminant validation and the reliability analysis of M-CHAT-R/F in the Chilean population. Patients and Method This is the second stage of the cross-cultural adaptation of cross-sectional design. M-CHATR/F was applied to a sample of 20 children with suspected ASD and 100 randomly selected healthy control children, aged between 16-30 months. Autism Diagnostic Observation Schedule (ADOS-2), considered as reference, was applied to the 20 patients of the clinical sample, to 20 children of the healthy control sample and to those cases of the healthy control sample with M-CHAT-R/F positive. Cronbach alpha was calculated, as well as M-CHAT-R/F and ADOS-2 correlation, sensitivity, and specificity analyses. Results: In the healthy sample, M-CHAT-R/F was positive in two patients, with one of them positive and the other one negative for ASD with ADOS-2 test. In the clinical sample, M-CHAT-R/F was positive in all cases, three of them were negative in the ADOS-2 test. The Alfa reliability of M-CHART-R/T was 0,889, the discriminant sensitivity and specificity were 100% and 98%, and the concurrent ones were 100% and 87.5% respectively. Conclusions: The Chilean M-CHAT-R/F version was reliable, sensitive and specific, similar to the original test, which opens the possibility for its use in clinical samples and for research. Validating M-CHAT-R/F is an ongoing process which must be further developed.
dc.fechaingreso.objetodigital2024-05-23
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.32641/rchped.v90i5.703
dc.identifier.eissn0717-6228
dc.identifier.issn0370-4106
dc.identifier.pubmedidMEDLINE:31859732
dc.identifier.urihttps://doi.org/10.32641/rchped.v90i5.703
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79963
dc.identifier.wosidWOS:000497977200005
dc.information.autorucFacultad de Medicina; Bronstein Croce, Jonathan; S/I; 227735
dc.issue.numero5
dc.language.isoes
dc.nota.accesocontenido completo
dc.pagina.final499
dc.pagina.inicio492
dc.publisherSOC CHILENA PEDIATRIA
dc.revistaREVISTA CHILENA DE PEDIATRIA-CHILE
dc.rightsacceso abierto
dc.subjectAutism
dc.subjectAutism Spectrum Disorder
dc.subjectScreening
dc.subjectChild Psychiatry
dc.subjectChild development
dc.subjectDISABILITIES MONITORING NETWORK
dc.subjectAGED 8 YEARS
dc.subjectMODIFIED CHECKLIST
dc.subjectUNITED-STATES
dc.subject11 SITES
dc.subjectTODDLERS
dc.subjectIDENTIFICATION
dc.subjectPREVALENCE
dc.subjectRISK
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleM-CHAT-R/F Validation as a screening tool for early detection in children with autism spectrum disorder
dc.typeartículo
dc.volumen90
sipa.codpersvinculados227735
sipa.indexWOS
sipa.indexPubmed
sipa.trazabilidadCarga SIPA;09-01-2024
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