Rathke’s cleft cyst infections and pituitary abscesses: case series and review of the literature

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dc.catalogadorpva
dc.contributor.authorAranda, F.
dc.contributor.authorGarcía, R.
dc.contributor.authorGuarda, F.J.
dc.contributor.authorNilo, F.
dc.contributor.authorCruz, J.P.
dc.contributor.authorCallejas, C.
dc.contributor.authorBalcells Marty, María Elvira
dc.contributor.authorGonzález, G.
dc.contributor.authorRojas, R.
dc.contributor.authorVillanueva, P.
dc.date.accessioned2023-11-06T15:43:05Z
dc.date.available2023-11-06T15:43:05Z
dc.date.issued2021
dc.description.abstractPurpose: Pituitary abscesses (PAs) are a rare clinical entity which may arise from normal pituitary tissue or underlying lesions within the gland. Rathke’s cleft cysts (RCCs) are not commonly associated with the development of PA. Methods: Retrospective chart review of three patients with PAs within RCCs at a single university center and review of the literature. Results: Three cases are reported. The first case presented with fever and headache and a history of prior surgery due to RCC and a recent respiratory tract infection. The second case had a history of recent skin infections and presented with sudden onset headache and hypopituitarism. In the third case, chronic visual field impairment prompted an ophthalmologic evaluation resulting in a diagnosis of an adenoma and an infected RCC. In all three cases, an endoscopic endonasal approach was performed to drain infected tissue and allowed microbiological identification of gram-positive cocci, followed by treatment with antibiotics for at least three weeks. Cases in the literature are scarce and the diagnosis is usually made intraoperatively due to non-specific manifestations and imaging. PAs arising from underlying pituitary lesions are less common than primary PAs. Differential diagnosis should include pituitary apoplexy, hypophysitis and other cystic lesions. Conclusion: PAs occurring in RCCs are infrequent. Clinical manifestations are commonly subacute, without septic symptoms. Imaging is usually non-specific. Preoperative diagnosis is infrequent and a broad differential diagnosis should be considered. Empirical antimicrobial therapy should be initiated and adjusted after obtaining cultures to reduce the rate of recurrence and improve clinical outcomes.
dc.fechaingreso.objetodigital2023-11-06
dc.fuente.origenScopus
dc.identifier.doi10.1007/s11102-020-01115-2
dc.identifier.eissn15737403
dc.identifier.eissn15737403
dc.identifier.issn1386341X
dc.identifier.pubmedid33433887
dc.identifier.scopusidSCOPUS_ID:85099219260
dc.identifier.urihttps://doi.org/10.1007/s11102-020-01115-2
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75228
dc.identifier.wosidWOS:000607368100005
dc.information.autorucEscuela de Medicina; Balcells Marty, María Elvira; 0000-0002-7223-9665; 7462
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final383
dc.pagina.inicio374
dc.publisherSpringer
dc.revistaPituitaryes_ES
dc.rightsacceso restringido
dc.subjectPituitary abscesses_ES
dc.subjectRathke’s cleft cystes_ES
dc.subjectHypopituitarismes_ES
dc.subjectPituitary tumorses_ES
dc.subjectEndoscopic endonasal approaches_ES
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRathke’s cleft cyst infections and pituitary abscesses: case series and review of the literaturees_ES
dc.typeartículo
dc.volumen24
sipa.codpersvinculados7462
sipa.indexWos
sipa.indexScopus
sipa.indexPubmed
sipa.trazabilidadScopus;12-10-2021
sipa.trazabilidadORCID;2023-11-06
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