Corticosteroid-induced osteoporosis in children: outcome after two-year follow-up, risk factors, densitometric predictive cut-off values for vertebral fractures
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Date
2007
Journal Title
Journal ISSN
Volume Title
Publisher
CLINICAL & EXPER RHEUMATOLOGY
Abstract
To identify factors that contribute to a decreased Z score of volumetric spine bone mineral density (ZvSBMD) and the development of vertebral fractures (VF) in children receiving chronic systemic corticosteroid therapy (SCT); to describe their outcome after 2 years, and to define predictive threshold values for ZvSBMD for VF.
Description
Keywords
corticosteroid-induced osteoporosis, methotrexate, growth retardation, physical activity, vertebral fractures, children, BONE-MINERAL DENSITY, GLUCOCORTICOID-INDUCED OSTEOPOROSIS, JUVENILE CHRONIC ARTHRITIS, X-RAY ABSORPTIOMETRY, VITAMIN-D DEFICIENCY, QUALITY-OF-LIFE, GROWTH-HORMONE, PHYSICAL-ACTIVITY, METABOLISM, MASS