Determinants of transhepatic cholesterol flux and their relevance for gallstone formation

Simple item page
dc.catalogadoryvc
dc.contributor.authorZanlungo Matsuhiro, Silvana
dc.contributor.authorRigotti Rivera, Attilio Gianpietro
dc.date.accessioned2024-06-06T19:19:45Z
dc.date.available2024-06-06T19:19:45Z
dc.date.issued2009
dc.description.abstractCholesterol available for bile secretion is controlled by a wide variety of proteins that mediate lipoprotein cholesterol uptake and cholesterol transport and metabolism in the liver. From a disease perspective, abnormalities in the transhepatic traffic of cholesterol from plasma into the bile may influence the risk of cholesterol gallstone formation. This review summarizes some recent progress in understanding the hepatic determinants of biliary cholesterol secretion and its potential pathogenic implications in cholesterol gallstone disease. This information together with new discoveries in this field may lead to improved risk evaluation, novel surrogate markers and earlier diagnosis, better preventive approaches and more effective pharmacological therapies for this prevalent human disease.
dc.fuente.origenORCID
dc.identifier.doi10.1111/j.1478-3231.2009.01972.x
dc.identifier.urihttps://doi.org/10.1111/j.1478-3231.2009.01972.x
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/86578
dc.information.autorucEscuela de Medicina;Zanlungo Matsuhiro, Silvana;0000-0001-8383-9829;72650
dc.information.autorucEscuela de Medicina;Rigotti Rivera, Attilio Gianpietro;0000-0002-0495-3525;68489
dc.language.isoen
dc.nota.accesocontenido parcial
dc.rightsacceso restringido
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleDeterminants of transhepatic cholesterol flux and their relevance for gallstone formation
dc.typeartículo
sipa.codpersvinculados72650
sipa.trazabilidadORCID;2024-06-03
Files
Collections
Artículos de revistas