Photosymbiosis for Biomedical Applications.

Simple item page
dc.catalogadorjca
dc.contributor.authorChávez, Myra N.
dc.contributor.authorMoellhoff, Nichola
dc.contributor.authorSchenck, T.
dc.contributor.authorEgaña, José Tomás
dc.contributor.authorNickelsen, J.
dc.date.accessioned2024-02-27T16:02:49Z
dc.date.available2024-02-27T16:02:49Z
dc.date.issued2020
dc.description.abstractWithout the sustained provision of adequate levels of oxygen by the cardiovascular system, the tissues of higher animals are incapable of maintaining normal metabolic activity, and hence cannot survive. The consequence of this evolutionarily suboptimal design is that humans are dependent on cardiovascular perfusion, and therefore highly susceptible to alterations in its normal function. However, hope may be at hand. “Photosynthetic strategies,” based on the recognition that photosynthesis is the source of all oxygen, offer a revolutionary and promising solution to pathologies related to tissue hypoxia. These approaches, which have been under development over the past 20 years, seek to harness photosynthetic microorganisms as a local and controllable source of oxygen to circumvent the need for blood perfusion to sustain tissue survival. To date, their applications extend from the in vitro creation of artificial human tissues to the photosynthetic maintenance of oxygen-deprived organs both in vivo and ex vivo, while their potential use in other medical approaches has just begun to be explored. This review provides an overview of the state of the art of photosynthetic technologies and its innovative applications, as well as an expert assessment of the major challenges and how they can be addressed.
dc.fechaingreso.objetodigital2024-03-25
dc.fuente.origenORCID
dc.identifier.doi10.3389/fbioe.2020.577204
dc.identifier.issn2296-4185
dc.identifier.urihttps://doi.org/10.3389/fbioe.2020.577204
dc.identifier.urihttp://europepmc.org/abstract/med/33123516
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/81355
dc.information.autorucInstituto de Ingeniería Biológica y Médica; Egaña Erazo, Jose Tomas; 0000-0003-2624-6992; 1018715
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final13
dc.pagina.inicio1
dc.revistaFrontiers in Bioengineering and Biotechnology
dc.rightsacceso abierto
dc.subjectTransgenic microalgae and cyanobacteria
dc.subjectPhotosynthetic oxygen
dc.subjectHypoxia
dc.subjectRegenerative medicine
dc.subjectTissue engineering
dc.subjectRecombinant proteins and monoclonal antibodies
dc.subject.ddc510
dc.subject.deweyMatemática física y químicaes_ES
dc.titlePhotosymbiosis for Biomedical Applications.
dc.typeartículo de revisión
dc.volumen8
sipa.codpersvinculados1018715
sipa.trazabilidadORCID;2024-01-15
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
fbioe-08-577204. Photosymbiosis for Biomedical Applications.pdf
Size:
1.09 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas