Reference values for inspiratory capacity in healthy nonsmokers over age 50 years

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dc.catalogadoryvc
dc.contributor.authorLisboa, Carmen
dc.contributor.authorLeiva, Alicia
dc.contributor.authorPinochet, Ramon
dc.contributor.authorRepetto, Paula
dc.contributor.authorBorzone, Gisella
dc.contributor.authorDiaz, Orlando
dc.date.accessioned2024-07-11T16:38:08Z
dc.date.available2024-07-11T16:38:08Z
dc.date.issued2007
dc.description.abstractObjective: The role of dynamic hyperinflation in triggering dyspnea and limiting exercise capacity in patients with chronic obstructive pulmonary disease has been recognized in recent years. The degree of dynamic hyperinflation can be assessed by measuring reduction in inspiratory capacity (IC). The aim of this study was to establish reference values for IC in healthy individuals of both sexes between the ages of 50 and 87 years, as such data are scarce in the literature. Subjects and methods: We studied 155 healthy volunteers (93 women) with normal spirometry. None had a prior history of respiratory, cardiovascular, or systemic diseases that might alter lung function. All were never-smokers. IC was measured during a normal, unforced inspiration to total lung capacity starting from functional residual capacity. The highest value of 6 satisfactory maneuvers was recorded. Sex, height, age, and weight were included in the regression equations. One thousand bootstrap samples for each sex were also analyzed. Results: For each sex, we found that a model including age, height, and weight produced IC prediction equations with a coefficient of determination (r2) of 0.414 for women and 0.447 for men. The mean (SD) intrasubject coefficient of variation was 4.3% (2%) for IC measured during a single session and 5.1% (0.4%) for measurements from 5 weekly sessions. Conclusions: Our results provide reference equations for IC that are valid for a healthy population over 50 years of age. Predicted values were similar to those recently obtained in an Italian population aged between 65 and 85 years.
dc.fechaingreso.objetodigital2024-07-12
dc.format.extent5
dc.fuente.origenWOS
dc.identifier.doi10.1016/S1579-2129(07)60112-8
dc.identifier.issn0300-2896
dc.identifier.pubmedidMEDLINE:17919414
dc.identifier.urihttps://doi.org/10.1016/S1579-2129(07)60112-8
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/87048
dc.identifier.wosidWOS:000249666200004
dc.issue.numero9
dc.language.isoes
dc.nota.accesocontenido parcial
dc.pagina.final489
dc.pagina.inicio485
dc.publisherEDICIONES DOYMA S/L
dc.revistaArchivos de Bronconeumología
dc.rightsacceso restringido
dc.subjectInspiratory capacity
dc.subjectReference values
dc.subjectSlow vital capacity
dc.subjectObstructive Pulmonary Disease
dc.subjectFlow Volume Curve
dc.subjectDynamic Hyperinflation
dc.subjectLung Hyperinflation
dc.subjectQuality Control
dc.subjectExercise
dc.subjectLimitation
dc.subjectSpirometry
dc.subjectBreathlessness
dc.subjectEquations
dc.titleReference values for inspiratory capacity in healthy nonsmokers over age 50 years
dc.typeartículo
dc.volumen43
sipa.trazabilidadWOS;05-06-2021
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