Effects of calcium supplementation on uteroplacental and fetoplacental blood flow in low-calcium-intake mothers: a randomized controlled trial

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dc.contributor.authorCarroli, Guillermo
dc.contributor.authorMerialdi, Mario
dc.contributor.authorWojdyla, Daniel
dc.contributor.authorAbalos, Edgardo
dc.contributor.authorCampodonico, Liana
dc.contributor.authorYao, Shih Ern
dc.contributor.authorGonzalez, Rogelio
dc.contributor.authorDeter, Russell
dc.contributor.authorLindheimer, Marshall
dc.contributor.authorVan Look, Paul
dc.date.accessioned2024-01-10T12:05:08Z
dc.date.available2024-01-10T12:05:08Z
dc.date.issued2010
dc.description.abstractOBJECTIVE: We postulated that calcium supplementation of calcium-deficient pregnant women would lower vascular resistance in uteroplacental and fetoplacental circulations.
dc.description.abstractSTUDY DESIGN: Pulsatility index (PI) and resistance index (RI) (uterine and umbilical arteries) and presence of bilateral uterine artery diastolic notching were assessed by Doppler ultrasound between 20-36 weeks' gestation in 510 healthy, nulliparous Argentinean women with deficient calcium intake in a randomized, placebo-controlled, double-blinded trial.
dc.description.abstractRESULTS: Average umbilical and uterine artery RI and PI tended to be lower in the supplemented group at each study week. Differences be-came statistically significant for umbilical artery RI and PI from 32 and 36 weeks, respectively. Estimated probabilities of bilateral uterine artery diastolic notching trended toward lower values in calcium-supplemented women.
dc.description.abstractCONCLUSION: Calcium supplementation of pregnant women with deficient calcium intake may affect uteroplacental and fetoplacental blood flow by preserving the vasodilation of normal gestation.
dc.fechaingreso.objetodigital2024-03-19
dc.format.extent9 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.ajog.2009.07.037
dc.identifier.eissn1097-6868
dc.identifier.issn0002-9378
dc.identifier.pubmedidMEDLINE:19716540
dc.identifier.urihttps://doi.org/10.1016/j.ajog.2009.07.037
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75954
dc.identifier.wosidWOS:000273026200010
dc.information.autorucMedicina;González R;S/I;55421
dc.issue.numero1
dc.language.isoen
dc.nota.accesoContenido parcial
dc.publisherMOSBY-ELSEVIER
dc.revistaAMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
dc.rightsacceso restringido
dc.subjectcalcium supplementation
dc.subjectDoppler velocimetry
dc.subjectpreeclampsia
dc.subjectPREGNANCY-INDUCED HYPERTENSION
dc.subjectINTRACELLULAR FREE CALCIUM
dc.subjectPREECLAMPSIA
dc.subjectMETABOLISM
dc.subject.ods05 Gender Equality
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa05 Igualdad de género
dc.subject.odspa03 Salud y bienestar
dc.titleEffects of calcium supplementation on uteroplacental and fetoplacental blood flow in low-calcium-intake mothers: a randomized controlled trial
dc.typeartículo
dc.volumen202
sipa.codpersvinculados55421
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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