Calorie Restriction and Time-Restricted Feeding: Effective Interventions in Overweight or Obese Patients Undergoing Radiotherapy Treatment with Curative Intent for Cancer

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dc.catalogadorjlo
dc.contributor.authorVega Huerta, Carmen Natalia
dc.contributor.authorBarnafi Wittwer, Esteban Andrés
dc.contributor.authorSánchez Rojel, César Giovanni
dc.contributor.authorAcevedo Claros, Francisco Nicolás
dc.contributor.authorWalbaum García, Benjamín Vicente
dc.contributor.authorParada Daza, Alejandra Cristina
dc.contributor.authorRivas Segura, Nicolás Eduardo
dc.contributor.authorMerino Lara, Tomás Rodrigo
dc.date.accessioned2024-03-27T13:32:02Z
dc.date.available2024-03-27T13:32:02Z
dc.date.issued2024
dc.description.abstractThis study assesses the feasibility of calorie restriction (CR) and time-restricted feeding (TRF) in overweight and obese cancer patients who realized little to no physical activity undergoing curative radiotherapy, structured as a prospective, interventional, non-randomized open-label clinical trial. Of the 27 participants initially enrolled, 21 patients with breast cancer were selected for analysis. The participants self-selected into two dietary interventions: TRF, comprising a sugar and saturated fat-free diet calibrated to individual energy needs consumed within an 8 h eating window followed by a 16 h fast, or CR, involving a 25% reduction in total caloric intake from energy expenditure distributed across 4 meals and 1 snack with 55% carbohydrates, 15% protein, and 30% fats, excluding sugars and saturated fats. The primary goal was to evaluate the feasibility of these diets in the specific patient group. The results indicate that both interventions are effective and statistically significant for weight loss and reducing one’s waist circumference, with TRF showing a potentially stronger impact and better adherence. Changes in the LDL, HDL, total cholesterol, triglycerides, glucose and insulin were not statistically significant.
dc.fechaingreso.objetodigital2024-04-02
dc.format.extent16 páginas
dc.fuente.origenORCID
dc.identifier.doi10.3390/nu16040477
dc.identifier.urihttp://dx.doi.org/10.3390/nu16040477
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/84755
dc.identifier.wosidWOS:001172593100001
dc.information.autorucEscuela de Medicina; Acevedo Claros, Francisco Nicolas; 0000-0003-3482-7746; 119540
dc.information.autorucEscuela de Medicina; Vega Huerta, Carmen Natalia; S/I; 1072996
dc.information.autorucEscuela de Medicina; Barnafi Wittwer, Esteban Andrés; 0009-0000-4814-2727; 1027988
dc.information.autorucEscuela de Medicina; Sánchez Rojel, César Giovanni; 0000-0002-2920-108X; 135644
dc.information.autorucEscuela de Medicina; Acevedo Claros, Francisco Nicolás; 0000-0003-3482-7746; 119540
dc.information.autorucEscuela de Medicina; Walbaum García, Benjamín Vicente; 0000-0003-2314-5360; 163702
dc.information.autorucEscuela de Medicina; Parada Daza, Alejandra Cristina; S/I; 127953
dc.information.autorucEscuela de Medicina; Rivas Segura, Nicolás Eduardo; S/I; 1067044
dc.information.autorucEscuela de Medicina; Merino Lara, Tomás Rodrigo; 0000-0003-3661-9123; 119017
dc.language.isoen
dc.nota.accesocontenido completo
dc.pagina.final16
dc.pagina.inicio1
dc.revistaNutrients
dc.rightsacceso abierto
dc.subjectIntermittent fasting
dc.subjectCancer
dc.subjectCurative
dc.subjectRadiotherapy
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCalorie Restriction and Time-Restricted Feeding: Effective Interventions in Overweight or Obese Patients Undergoing Radiotherapy Treatment with Curative Intent for Cancer
dc.typeartículo
dc.volumen16
sipa.codpersvinculados119540
sipa.codpersvinculados1072996
sipa.codpersvinculados1027988
sipa.codpersvinculados135644
sipa.codpersvinculados163702
sipa.codpersvinculados127953
sipa.codpersvinculados1067044
sipa.codpersvinculados119017
sipa.trazabilidadORCID;2024-03-25
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